The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS). Its name is derived from its ability to be activated by the artificial glutamate analog AMPA. The receptor was discovered by Tage Honore and colleagues at the School of Pharmacy in Copenhagen, and published in 1982 in the Journal of Neurochemistry. AMPARs are found in many parts of the brain and are the most commonly found receptor in the nervous system. The AMPA receptor GluA2 (GluR2) tetramer was the first and currently only glutamate receptor ion channel to be crystallized.

AMPARs are composed of four types of subunits, designated as GluR1 (GRIA1), GluR2 (GRIA2), GluR3 (GRIA3), and GluR4, alternatively called GluRA-D2 (GRIA4), which combine to form tetramers. Most AMPARs are heterotetrameric, consisting of symmetric 'dimer of dimers' of GluR2 and either GluR1, GluR3 or GluR4. Dimerization starts in the Endoplasmic reticulum with the interaction of n-terminal LIVBP domains, then "zips up" through the ligand-binding domain into the transmembrane ion pore.

Daniel Choquet (born 1962) is a French neuroscientist.

Daniel Choquet is the son of the physicist Yvonne Choquet-Bruhat and the mathematician Gustave Choquet. He is the grand-son of the physicist Georges Bruhat. He obtained his bachelor's degree in 1979, followed by a degree in bioengineering from École centrale Paris in 1984. He obtained his P.hD. in 1988 from Pierre and Marie Curie University and studied pharmacology at the Pasteur Institute. That year, he started working for the French National Centre for Scientific Research (CNRS). From 1994 to 1996, he was a post-doctoral fellow at Duke University. The following year, in 1997, he was promoted to research director at the CNRS. He is the director of the Bordeaux Imaging Center and the Interdisciplinary Institute for Neuroscience. He was elected as a member of the French Academy of Sciences November 30, 2010.

Choquet is a biologist, focusing on nanoscopic imaging and the organization of receptors in neurons. His early research included work on the properties of ion channels of B lymphocytes. This research work earned him the bronze medal at CNRS in 1990. During his post-doc at Duke, he discovered that cells can respond and adapt to the mechanical properties of their environment.