- published: 02 Aug 2007
- views: 46119
Paclitaxel is a drug used to treat ovarian, breast, lung, pancreatic and other cancers. It and docetaxel represent the taxane family of drugs. Paclitaxel's mechanism of action involves interference with the normal breakdown of microtubules during cell division.
Common side effects include: hair loss, muscle and joint pains, and diarrhea, among others. It results in a greater risk of infections which can be potentially serious. Use during pregnancy often results in problems in the infant.
Paclitaxel was discovered beginning in 1962 as a result of a U.S. National Cancer Institute-funded screening program; being isolated from the bark of the Pacific yew, Taxus brevifolia, thus its name "taxol". Developed commercially by Bristol-Myers Squibb, the generic name has changed to "paclitaxel" with a trademark becoming Taxol. Other trademarks include Abraxane. Clinicians sometimes use the abbreviation "PTX" for paclitaxel, which is discouraged, because it is not a unique identifier.
Paclitaxel is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. There was initially concern over the environmental impact of its initial sourcing from the slow growing Pacific yew. In addition, both the assignment of rights to Bristol-Myers Squibb and the product name were subject to public debate and Congressional hearings.
For more information, visit CancerQuest at http://www.cancerquest.org/drugs/paclitaxel. The anti-cancer drug Taxol works by interfering with processes within cells. The way in which Taxol binds to microtubule and prevents cell division is shown in this animation. For further information, visit http://www.cancerquest.org
This video describes the schedule and treatment with Carboplatin/taxol chemotherapy for cancer. You should first watch the general information chemotherapy video on the charlottecancer channel before viewing this.
This video documents the day before through several days after my first chemotherapy treatment with the drug Taxol. More of my story, and more of my cute puppy, on my blog: http://babiesornot.blogspot.com
A human breast cancer cell treated with the drug paclitaxel attempts to divide. Scientists have learned that, instead of halting cell division, the drug causes chromosomes (red) to be pulled in multiple directions. The tug-of-war scrambles the cells' DNA and leads to cell death. Read more at sciencenews.org Credit: Lauren M. Zasadil and B.A. Weaver
Shot at 20 frames per second. So that's 4820 pictures. Needless to say, this process topped out my hd. This video was made without a tripod (instead, a jury-rigged cardboard box) so it's a bit shaky. First stop motion try too. The beginning of the video is a parody of/homage to the opening of one of my favorite movies, Stanley Kubrick's 2001: A Space Odyssey. If you liked it, click like. If you didn't like, I encourage you to click that one too. Oh yeah, and it's a school project at UT Austin for my chemistry lab. Hope you enjoy it ps- the banjo was recorded using garage band and a mac, sound it sounds pretty bad.
Taxol
Nalie's Last Chemo Ever! A total of 16 rounds of chemotherapy. 4 A/C once every 3 weeks and 12 Taxol once a week. 6 months of treatments and symptoms. My body changed, my health changed but nothing took away my smile.
Understandings: Taxol is a drug that is commonly used to treat several different forms of cancer. Taxol naturally occurs in yew trees but is now commonly synthetically produced. Applications and skills: Explanation of how taxol (paclitaxel) is obtained and used as a chemotherapeutic agent.
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Taxloss lover still lives in the war
Taxloss lover touching 74
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Just remember that we said we'd deliver you
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And then you'll be mine and we'll fly somewhere sunny
And you'll quibble that our drivel seems unsatifactory
You're a taxloss, come back to me
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Your taxloss lover and he's always a flirt
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Your taxloss lover wears a cracking dress
Sign on the line and we'll give you the money
And then you'll be mine and we'll fly somewhere sunny
You'll quibble that our drivel seems unsatifactory
We're a taxloss, come back to me
We want your money, taxloss
Sign on the line and we'll give you the money
And then you'll be mine and we'll fly somewhere sunny
And you'll quibble that our drivel seems unsatifactory
A taxloss, come back to me
We want your money, taxloss
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Junk pop, chart hop
Mop top, swap shop
Who'd you nick your cliche off?