In music, homophony ( /hɵˈmɒfəni/; Greek: ὁμόφωνος, homóphōnos, from ὁμός, homós, "same" and φωνή, phōnē, "sound, tone") is a texture in which two or more parts move together in harmony, the relationship between them creating chords. This is distinct from polyphony, in which parts move with rhythmic independence, and monophony, in which all parts (if there are multiple parts) move in parallel rhythm and pitch. A homophonic texture is also homorhythmic (or uses a "very similar rhythm"). However, in melody-dominated homophony, one voice, often the highest, plays a distinct melody, and the accompanying voices work together to articulate an underlying harmony. Initially, in Ancient Greece, homophony indicated music in which a single melody is performed by two or more voices in unison or octaves, i.e. monophony with multiple voices.

Homophony as a term first appeared in English with Charles Burney in 1776, emphasizing the concord of harmonized melody.

While homophony can be heard in nearly all European musical traditions, the first notated examples appeared during the Medieval period in dance music, such as the Estampie. However, because manuscript was expensive to produce, there is little record of Medieval homophony, most notated music being monophonic. There was similarly little record of homophony during the Renaissance period.