DSN may refer to:

• Data set (IBM mainframe) Name, the name of a computer file having a record organization
• Data Source Name, a data structure used to describe a connection to a data source
• Deep Space Network, a communication network that supports interplanetary spacecraft missions
• Star Trek: Deep Space Nine, a science fiction television program that originally aired from 1993 to 1999
• Defense Switched Network, a communications network operated by the United States Department of Defense
• Delivery Status Notification message, an automated electronic mail message about a delivery problem
• Distributed social network[ing], a social network that is decentralised and distributed across multiple providers.
• International Conference on Dependable Systems and Networks, an annual conference on dependable computer systems and reliable networks
• DSN DASH, the U.S. Navy's Drone Anti-Submarine Helicopter.

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