Splice (film)

Splice is a 2009 Canadian-French science fiction horror film directed by Vincenzo Natali and starring Adrien Brody, Sarah Polley, and Delphine Chanéac. The story concerns experiments in genetic engineering being done by a young scientific couple, who attempt to introduce human DNA into their work of splicing animal genes.Guillermo del Toro, Don Murphy, and Joel Silver executive produced.

Plot

Genetic engineers Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) hope to achieve fame by splicing animal DNA to create hybrids for medical use at the company N.E.R.D. (short for Nucleic Exchange Research and Development). Their work previously yielded Fred, a dog-sized vermiform creature intended as a mate for their female specimen, Ginger. After successfully mating them, Clive and Elsa plan to create a human-animal hybrid that could revolutionize science. Their employers Joan Chorot (Simona Maicanescu) of N.E.R.D. and William Barlow (David Hewlett) forbid them to do this. Instead, they are to find and extract proteins used for commercial drug production from Fred and Ginger. Clive and Elsa pursue their own agenda in secret. They develop a viable female creature (Abigail Chu).