Nova Zagora (Bulgarian: Нова Загора) is a town located in the southeastern plains of Bulgaria in Sliven Province. It is the administrative centre of Nova Zagora Municipality. As of December 2009, the town has a population of 23,625 inhabitants, while the entire municipality (including surrounding villages) has a population of 45,111.

The first traces of life in the region date back thousands of years. Many archeological sites are located in the region, showing settlements dating back to the Stone Age and the Stone-Copper age (Eneolithic). The most prominent archeological site is in the nearby village of Karanovo. The Nova Zagora Historical Museum has many historically significant artifacts dating back to this era.

The region is very fertile, growing a wide range of produce including grapes, sunflowers and cereals. The municipality has a manufacturing base including machine tools producer ZMM Ltd., agriculture equipment maker Perla Ltd., and textile manufacturer Miroglio Ltd.

Nova Zagora is located on the main Sofia-Plovdiv-Burgas railroad, as well as the Trakia Highway that runs from Sofia to Burgas. It is 35 km east of Stara Zagora and 30 km west of Sliven. The Nova Zagora Municipality is part of the Sliven administrative district.