WFDC-DT

WFDC-DT, virtual channel 14 (UHF digital channel 15) is a Univision owned-and-operated television station licensed to Arlington, Virginia and serving Washington, District of Columbia. The station is owned by Univision Communications and managed by Entravision Communications; this makes WFDC a sister station to UniMás affiliate WMDO-CD (channel 47). The two stations share studios located in Washington, and its transmitter is located in the Tenleytown section of Washington's northwest quadrant.

On cable, the station is carried on Xfinity channel 14 in the Washington area and on channel 11 in Baltimore (the latter market's NBC affiliate, WBAL-TV, broadcasts over-the-air on channel 11, but is carried on channel 21 due to signal issues).

History

Prior history of channel 14 in Washington

Channel 14 first signed on as WOOK on March 6, 1963 as the first television station in the country aimed at the African-American demographic. WOOK's claim to fame was their teen-oriented dance show called Teenarama, which featured big-name acts such as James Brown and Marvin Gaye. In 1969, the station changed its call letters, to WFAN-TV (the WFAN call letters are now used on a radio station at 660 AM in New York City). From 1968 to 1972, channel 14 was the sister station to WMET (channel 24) in Baltimore, Maryland. Both stations were owned by United Broadcasting.

WFDC5

WAP four-disulfide core domain protein 5 is a protein that in humans is encoded by the WFDC5 gene.

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.

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Further reading

WFDC1

WAP four-disulfide core domain protein 1 is a protein that in humans is encoded by the WFDC1 gene.

This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

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Further reading