Dushanbe (Tajik: Душанбе, Dushanbe, Dyushambe until 1929; Stalinabad, Tajik: Сталинабад until 1961), population 679,400 people (2008 est.), is the capital and largest city of Tajikistan. Dushanbe means "Monday" in Tajik, and the name reflects the fact that the city grew on the site of a village that originally was a popular Monday marketplace.

Situated at the confluence of two rivers, Varzob and Kofarnihon, Dushanbe is the capital of Tajikistan. Although archaeological remnants dating to the 5th century BC have been discovered in the area, there is little to suggest that Dushanbe was more than a small village until the early 20th century. In 1920, the last Emir of Bukhara briefly took refuge in Dushanbe (then called Dyushambe) after being overthrown by the Bolshevik revolution. He fled to Afghanistan after the Red Army conquered the area the next year.

Dushanbe, which means "Monday" in Persian, (فارسی), developed on the site of a Monday marketplace village, Dyushambe-Bozor, and its former name Dyushambe was a Russified version of the word meaning "Monday" in Persian (du-shanbe from du two + shanbe Saturday, lit. "second day after Saturday"). Following the Red Army victory in Central Asia the village was upgraded to town in 1925 and made the capital of the newly created Tajik Autonomous Soviet Socialist Republic (Tajik ASSR). After the transformation of Tajik ASSR to Tajik Soviet Socialist Republic (Tajik SSR) in 1929, Dyushambe was renamed Stalinabad, after Joseph Stalin. As part of Nikita Khrushchev's de-Stalinization initiative, the city was renamed Dushanbe in 1961.