The Ganden Tripa or Gaden Tripa (tib. dGa’-ldan Khri-pa) ("Holder of the Ganden Throne") is the title of the spiritual leader of the Gelug (Dge-lugs) school of Tibetan Buddhism, the school which controlled central Tibet from the mid-17th century until 1950s. He is identical with the respective abbot of Ganden Monastery. The present head of the Gelugpa order is Thubten Nyima Lungtok Tenzin Norbu, the 102nd Ganden Tripa and not, as is often misunderstood, the Dalai Lama.

The Ganden Tripa is an appointed office, not a reincarnation lineage. It is awarded on the basis of competitive examination. Since the position is held for only a 7-year term, there have been many more Ganden Tripas than Dalai Lamas to date (102 as against 14).

Either Tsongkapa (Tsong-ka-pa) (1357–1419), who founded the Gelug sect, or his successor, Gyaltsab Je (Rgyal-tshab-rje), may be considered to have been the first Ganden Tripa. (After Tsongkhapa's passing, his teachings were held and kept by Gyaltsab Je and Khedrub Je who were the next abbots of Ganden monastery. The lineage has been held by the Ganden Tripas–the throne-holders of Ganden Monastery.)

The Dalai Lama is a high lama in the Gelug or "Yellow Hat" branch of Tibetan Buddhism. The name is a combination of the Sino-Mongolian word далай (dalai) meaning "Ocean" and the Tibetan word བླ་མ་ bla-ma (with a silent "b") meaning "chief, high priest".

In religious terms, the Dalai Lama is believed by his devotees to be the rebirth of a long line of tulkus who are considered to be manifestations of the bodhisattva of compassion, Avalokiteśvara. Traditionally, the Dalai Lama is thought of as the latest reincarnation of a series of spiritual leaders who have chosen to be reborn in order to enlighten others. The Dalai Lama is often thought to be the leader of the Gelug School, but this position belongs officially to the Ganden Tripa, which is a temporary position appointed by the Dalai Lama who, in practice, exerts much influence. The line of Dalai Lamas began as a lineage of spiritual teachers; the 5th Dalai Lama assumed political authority over Tibet.

For certain periods between the 17th century and 1959, the Dalai Lamas sometimes directed the Tibetan government, which administered portions of Tibet from Lhasa. The 14th Dalai Lama remained the head of state for the Central Tibetan Administration ("Tibetan government in exile") until his retirement on March 14, 2011. He has indicated that the institution of the Dalai Lama may be abolished in the future, and also that the next Dalai Lama may be found outside Tibet and may be female. The Chinese government was very quick to reject this and claimed that only it has the authority to select the next Dalai Lama.