Khuzestan Province (Persian: استان خوزستان‎, Ostān-e Khūzestān is one of the 31 provinces of Iran. It is in the southwest of the country, bordering Iraq's Basra Province and the Persian Gulf. Its capital is Ahwaz and covers an area of 63,238 km². Other major cities include Behbahan, Abadan, Andimeshk, Khorramshahr, Bandar Imam, Dezful, Shushtar, Omidiyeh, Izeh, Baq-e-Malek, Mah Shahr, Dasht-i Mishan/Dasht-e-Azadegan, Ramhormoz, Shadegan, Susa, Masjed Soleiman, Minoo Island and Hoveizeh.

Historically, Khuzestan is what historians refer to as ancient Elam, whose capital was in Susa. The Achaemenid Old Persian term for Elam was Hujiyā, which is present in the modern name. Khuzestan, meaning "the Land of the Khuz" refers to the original inhabitants of this province, the "Susian" people (Old Persian "Huza" or Huja (as in the inscription at the tomb of King Darius I at Naqsh-e Rostam, (the Shushan of the Hebrew sources) where it is recorded as inscription as "Hauja" or "Huja"). This is in conformity with the same evolutionary process where the Old Persian changed the name Sindh into Hind/Hindustan. In Middle Persian the term evolves into "Khuz" and "Kuzi" The pre-Islamic Partho-Sassanid Inscriptions gives the name of the province as Khwuzestan. As the most ancient Iranian province, it is often referred to as the "birthplace of the nation," as this is where the history of the Persian Empire begins.