UFC 76: Knockout was a mixed martial arts (MMA) event held by the Ultimate Fighting Championship (UFC). The event took place on September 22, 2007 at the Honda Center in Anaheim, California. Though the event was subtitled Knockout, the entire card produced no knockouts.

The main event was anticipated to be Chuck Liddell versus Wanderlei Silva, a long-awaited match between the two popular former champions of the UFC and PRIDE, respectively; however, the main event featured a fight between former UFC light heavyweight champion Chuck Liddell and The Ultimate Fighter 2 alum Keith Jardine, with both fighters returning from knockout losses at UFC 71.

Also appearing on the card was PRIDE 2005 Middleweight Grand Prix champion & future UFC Light Heavyweight Champion Mauricio "Shogun" Rua, who made his Octagon debut against The Ultimate Fighter 1 winner Forrest Griffin.

Welterweight Diego Sanchez returned after his decision loss at UFC 69 to Josh Koscheck when he faced Jon Fitch, a training partner of Koscheck and a former Purdue University wrestler who was in the midst of a thirteen-fight win streak.

Charles David "Chuck" Liddell (born December 17, 1969) is a retired American mixed martial artist and former Ultimate Fighting Championship light heavyweight champion. Liddell has an extensive striking background in Kempo, Koei-Kan karate and kickboxing, as well as a grappling background in collegiate wrestling. Liddell is known for his Knockout power, Iron chin, Excellent counter striking and for his sprawl-and-brawl technique, which made him one of the most difficult fighters to takedown. He is one of the most dominant champions that ever competed in the UFC. He still holds the record for the most knockouts in UFC history. As of his retirement, Liddell has had 23 fights in the UFC. Along with fellow UFC Hall of Fame fighter Randy Couture, Liddell is widely credited for bringing mixed martial arts into the mainstream of American sports and entertainment. On July 10, 2009, he was inducted into the UFC Hall of Fame.

Liddell began studying Koei-Kan karate at the age of 12; the tattoo seen on his scalp reads "Koei-Kan". Liddell was a four-year starter on the football team at San Marcos High School. While growing up in Santa Barbara, he often frequented the infamous Del Playa Drive, the middle of the party scene of the college town of Isla Vista, where he often found himself in fights with drunk college students. He became a Division I wrestler at California Polytechnic State University, San Luis Obispo and graduated with a Bachelor of Arts Degree in Business/Accounting in 1995. He holds an amateur kickboxing record of 20 wins and 2 losses, with 16 of his wins coming by way of knockout.

Diego J. Sanchez (born December 31, 1981) is an American mixed martial artist (MMA) of Mexican descent, with a background in wrestling and Gaidojutsu, system of submission wrestling developed by his longtime trainer Greg Jackson. He currently fights as a welterweight with the Ultimate Fighting Championship (UFC). Sanchez is currently ranked as the #9 welterweight fighter in the world by MMAWeekly.

Sanchez was born in Albuquerque, New Mexico. He attended Del Norte High School, where he became a state champion wrestler.^{[citation needed]}

Diego Sanchez wrestled in New Mexico before starting training MMA while working for UPS. Sanchez eventually joined Jackson's Submission Fighting, still while working for UPS, managing the time between work and training. In 2002, he made his MMA debut for King of the Cage where he also later became a champion.

His UFC debut came when he was chosen as a participant on the first season of the reality show, The Ultimate Fighter. Presented as a young, focused middleweight who only had one goal, to become a UFC champion, he won a contract with the UFC after winning a fight against Kenny Florian, becoming the middleweight winner for the first season of the show. On the show, Sanchez was known for being the "odd-ball" of the group, practicing yoga at odd moments and trying to extract "energy" from a lightning storm, and was also a self-proclaimed "Zen master". Sanchez' last fight before his loss to Josh Koscheck was against Joe Riggs on December 13, 2006 at UFC Fight Night 7. Sanchez landed a right hook that knocked Riggs down, followed by a running knee that knocked Riggs out. Sanchez won at 1:45 of the first round, scoring the first UFC knockout of his career.