Sydney Brenner, CH FRS (born 13 January 1927) is a South African biologist and a 2002 Nobel prize in Physiology or Medicine laureate, shared with H. Robert Horvitz and John Sulston.

Brenner made significant contributions to work on the genetic code, and other areas of molecular biology.

He established the roundworm Caenorhabditis elegans as a model organism for the investigation of developmental biology, and founded the Molecular Sciences Institute in Berkeley, California, U.S..

Brenner was born in the small town of Germiston, South Africa. His parents were Jewish immigrants. His father came to South Africa from Lithuania in 1910, and his mother, from Riga, Latvia, in 1922. Educated at Germiston High School and the University of the Witwatersrand, he went on to complete a D.Phil. from Exeter College, Oxford.

He was married to Dr. May Brenner (née Covitz, subsequently Balkind) from December 1952 until her death in January 2010; their children include Belinda, Carla, Stefan, and his stepson Jonathan Balkind from his wife's first marriage. He lives in Ely, Cambridgeshire.

Sydney ( /sɪdni/) is the most populous city in Australia and the state capital of New South Wales. Sydney is classified as an Alpha+ World City indicating its influence in the region and throughout the world.

Sydney is located on Australia's south-east coast of the Tasman Sea. As of June 2010, the greater metropolitan area had an approximate population of 4.6 million people. Inhabitants of Sydney are called Sydneysiders, comprising a cosmopolitan and international population.

The site of the first British colony in Australia, Sydney was established in 1788 at Sydney Cove by Arthur Phillip, commodore of the First Fleet as a penal colony. The city is built on hills surrounding Port Jackson which is commonly known as Sydney Harbour, where the iconic Sydney Opera House and the Harbour Bridge feature prominently. The hinterland of the metropolitan area is surrounded by national parks, and the coastal regions feature many bays, rivers, inlets and beaches including the famous Bondi Beach and Manly Beach. Within the city are many notable parks, including Hyde Park and the Royal Botanic Gardens.