DLX3
Homeobox protein DLX-3 is a protein that in humans is encoded by the DLX3 gene.
Function
Dlx3 is a crucial regulator of hair follicle differentiation and cycling. Specifically, colocalization of phosphorylated Smad1 / 5 / 8 complex and Dlx3 regulate role for BMP signaling to Dlx3 during hair morphogenesis in animal models.
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17.
Clinical significance
Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome (TDO) and amelogenesis imperfecta with taurodontism.
Podcasts:
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by Bella Thorne
Ttylxox
by: Bella ThorneWatch this!
Be, be, be my BFF
'Cause IDK what's coming next
And I'll be LMHO with the rest
So TTYLXOX
C'mon!
Be, be, be my BFF (haha...)
'Cause IDK what's coming next
And I'll be LMHO with the rest
So TTYLXOX
Show up in the same dress
We don't know who wore it best
Not make a big deal
Act like it's a new trend
Look good when we go 'round here
Try on these boots, I found
This boy who said you're sweet
He's got a best friend!
(Think you'll always be mine...)
Be, be, be my BFF
'Cause IDK what's coming next
And I'll be LMHO with the rest
So TTYLXOX
Be, be, be my BFF
'Cause IDK what's coming next
And I'll be LMHO with the rest
So TTYLXOX, XOX!
I'm a better me when
You're here next to me
LJK can't you tell we're
ROTFL
Who needs words when we got
Hearts, smile
T-t-t-time goes by so fast
But we are meant to last...
(Think you'll always be mine...)
Be, be, be my BFF
'Cause IDK what's coming next
And I'll be LMHO with the rest
So TTYLXOX
Be, be, be my BFF
'Cause IDK what's coming next
And I'll be LMHO with the rest
So TTYLXOX, XOX!
(TTYLXOX!)
C'mon!
(Think you'll always be mine...)
Be, be, be my BFF
'Cause IDK what's coming next
And I'll be LMHO with the rest
So TTYLXOX, (XOX!)
Be, be, be my BFF
'Cause IDK what's coming next (c'mon!)
And I'll be LMHO with the rest
So TTYLXOX, XOX!
Be, be, be my BFF
'Cause IDK what's coming next
And I'll be LMHO with the rest
So TTYLXOX, (XOX!)
Be, be, be my BFF
'Cause IDK what's coming next
And I'll be LMHO with the rest