- published: 26 Apr 2015
- views: 30
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Video shows what inosinic acid means. a nucleotide, inosine phosphate, found in muscle tissue. inosinic acid synonyms: E630 when used as a flavour enhancer. Inosinic acid Meaning. How to pronounce, definition audio dictionary. How to say inosinic acid. Powered by MaryTTS, Wiktionary
Biosynthesis of purines (adenosine and guanine) from ribose-5-phosphate (this occurs in the cytoplasm of every cell, but mostly in the liver).
Correction: the ribose-5-phosphate using ATP to the 5-phosphpribosyl-1-pyrophosphate becomes AMP, not ADP like I wrote up. And its guanosine* not guanine monophosphate. Missing step in video but still important - IMP is converted to adenlylosuccinate before being converted to AMP.
Not explained in video but still important - Regulation of Purine Synthesis:
- AMP and GMP inhibit amido-transferase.
- AMP and GMP also inhibit their own formation by feedback inhibition of adenylosuccinate synthetase and IMP dehydrogenase.
- The availability of PRPP (phosphoribosyl-1-pyrophosphate) is also a modulatory factor.
First I go over the most important steps, then I list every single step in the pathway.
- published: 30 Apr 2016
- views: 570
In this episode, we'll be making rice with healthy chicken breast and umeboshi pickled plums. We'll be cooking the chicken rare, to help it keep its flavor, with green shiso leaves and a refreshing ume plum sauce. For a side dish, we'll be making egg drop soup, using the water we cooked the chicken in. With the glutamic acid from kombu kelp and the inosinic acid from the chicken, this soup has plenty of umami for a rich, delicious flavor. We'll also be making potato salad with green beans. This simple salad is made by lightly boiling our vegetables, then adding a special sauce made with mayonnaise and wasabi.
- published: 11 Oct 2016
- views: 16
Disodium inosinate is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. It is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks.
This video is targeted to blind users.
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- published: 22 Dec 2015
- views: 104
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409
4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1
6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all
7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html
8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB
9. Course materials at http://oregonstate.edu/instruct/bb451
Nucleotide Metabolism
1. Nucleotides consist of a) sugar, b) nitrogenous base, and c) phosphate
2. Nucleosides consist of a a) sugar and b) nitrogenous base
3. The sugars of nucleosides and nucleotides are either ribose (found in ribonucleotides of RNA) or deoxyribose (found in deoxyribonucleotides of DNA).
4. Unless otherwise specified, the term "nucleoside" will be used in this class to indicate either ribonucleosides (contain ribose) or deoxyribonucleosides (contain deoxyribose).
5. The term nucleoside phosphate is equivalent to a nucleotide (nucleoside + phosphate + base = nucleotide). This is true whether it is a monophosphate, diphosphate, or triphosphate.
6. The nitrogenous bases found in nucleotides include adenine (purine), guanine (purine), thymine (pyrimidine), cytosine (pyrimidine), and uracil (pyrimidine).
7. The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism.
8. Ribonucleotides are the building blocks of RNA and deoxyribonucleotides are the building blocks of DNA.
9. Nucleotides and nucleosides are made in cells by 1) salvage pathways or 2) de novo pathways.
10. In salvage pathways, nucleic acids can be broken down to nucleoside monophosphates or individual bases. Monophosphates be rephosphorylated to triphosphates. Alternatively, nucleoside monophosphates can lose a phosphate (becoming nucleosides) or can lose the phosphate and the sugar to become a base.
11. In de novo synthesis of nucleotides, ribonucleotides are synthesized first. Deoxyribonucleotides are made from ribonucleoside diphosphates. Atoms in the ring of pyrimidines come from aspartate and carbamoyl phosphate.
12. The enzyme carbamoyl phosphate synthetase has a catalytic strategy involving channeling of the substrates through the enzyme as catalysis occurs. This is important because some of the intermediates (such as carboxyphosphate and carbamic acid) are very unstable in aqueous solution.
13. The most important regulatory enzyme for the pathway of pyrimidine biosynthesis is ATCase, which plays an important role in balancing the amounts of purines and pyrimidines. The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate.
14. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP.
15. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate.
16. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP.
17. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present.
18. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle.
19. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate).
20. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP.
21. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released.
22. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. Nucleoside diphosphate kinase (NDP kinase or NDPK) converts all nucleoside diphosphates to nucleoside triphosphates.
- published: 10 Feb 2012
- views: 10480
巨大サイズのキンキの開き。根室の潮風が最高のスパイス！
Huge size of cut-open and dried Channel Rockfish.
This is traditional method of food preservation. Moreover, it makes more "Inosinic acid," which is one of the element of "Umami."
This is how NemuRock does it baby!!
- published: 13 May 2016
- views: 40
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409
4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1
6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all
7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html
8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB
9. Course materials at http://oregonstate.edu/instruct/bb451
Nucleotide Metabolism
1. Nucleotides consist of a) sugar, b) nitrogenous base, and c) phosphate
2. Nucleosides consist of a a) sugar and b) nitrogenous base
3. The sugars of nucleosides and nucleotides are either ribose (found in ribonucleotides of RNA) or deoxyribose (found in deoxyribonucleotides of DNA).
4. Unless otherwise specified, the term "nucleoside" will be used in this class to indicate either ribonucleosides (contain ribose) or deoxyribonucleosides (contain deoxyribose).
5. The term nucleoside phosphate is equivalent to a nucleotide (nucleoside + phosphate + base = nucleotide). This is true whether it is a monophosphate, diphosphate, or triphosphate.
6. The nitrogenous bases found in nucleotides include adenine (purine), guanine (purine), thymine (pyrimidine), cytosine (pyrimidine), and uracil (pyrimidine).
7. The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism.
8. Ribonucleotides are the building blocks of RNA and deoxyribonucleotides are the building blocks of DNA.
9. Nucleotides and nucleosides are made in cells by 1) salvage pathways or 2) de novo pathways.
10. In salvage pathways, nucleic acids can be broken down to nucleoside monophosphates or individual bases. Monophosphates be rephosphorylated to triphosphates. Alternatively, nucleoside monophosphates can lose a phosphate (becoming nucleosides) or can lose the phosphate and the sugar to become a base.
11. In de novo synthesis of nucleotides, ribonucleotides are synthesized first. Deoxyribonucleotides are made from ribonucleoside diphosphates. Atoms in the ring of pyrimidines come from aspartate and carbamoyl phosphate.
12. The enzyme carbamoyl phosphate synthetase has a catalytic strategy involving channeling of the substrates through the enzyme as catalysis occurs. This is important because some of the intermediates (such as carboxyphosphate and carbamic acid) are very unstable in aqueous solution.
13. The most important regulatory enzyme for the pathway of pyrimidine biosynthesis is ATCase, which plays an important role in balancing the amounts of purines and pyrimidines. The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate.
14. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP.
15. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate.
16. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP.
17. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present.
18. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle.
19. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate).
20. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP.
21. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released.
22. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. Nucleoside diphosphate kinase (NDP kinase or NDPK) converts all nucleoside diphosphates to nucleoside triphosphates.
- published: 03 Aug 2011
- views: 6399
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409
4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
5. Lecturio videos for medical students - https://www.lecturio.com/medical-courses/biochemistry.course
6. Course video channel at http://www.youtube.com/user/oharow/videos?view=1
7. Check out all of my free workshops at http://oregonstate.edu/dept/biochem/ahern/123.html
8. Check out my Metabolic Melodies at http://www.davincipress.com/
9. My courses can be taken for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB
10. Course materials at http://oregonstate.edu/instruct/bb451
Highlights - Nucleotide Metabolism II
1. The most important regulatory enzyme for the entire pathway of pyrimidine biosynthesis is aspartate transcarbamoylase (ATCase), which plays an important role in balancing the amounts of purines and pyrimidines and also measuring the amount of energy available (via the amount of ATP present). The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate and is allosterically activated by ATP and allosterically inactivated by CTP.
2. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP.
3. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate, but all diphosphates (purines, pyrimidines, and all deoxyribonucleoside diphosphates) are converted to triphosphates by NDPK.
4. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP, thus providing a balance between the amount of CTP and UTP.
5. De novo synthesis of purines uses atoms from aspartate, glycine, glutamine, carbon dioxide, and tetrahyrdofolate derivatives to make the purine ring.
6. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present. This enzyme helps to control purine production and also slows purine production when one nucleotide gets to be in too high of a concentration.
7. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle.
8. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate).
9. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP. Thus, the critical balance of these two nucleotides is maintained using this scheme.
10. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released.
11. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. These enzymes include AMP kinase (also called adenylate kinase) and GMP kinase (also called guanylate kinase), which convert nucleoside monophosphates to nucleoside diphosphates, and nucleoside diphosphate kinase (NDP kinase or NDPK), which converts all nucleoside diphosphates to nucleoside triphosphates.
12. Deoxyribonucleotides are made starting with ribonucleotide reductase (RNR). It catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates (for example, ADP to dADP). RNR works on all of the ribonucleoside diphosphates. NDPK converts all of the nucleoside diphosphates to nucleoside triphosphates using energy from other triphosphates.
13. The pathway to making thymidine nucleotides is more complicated. It goes from UDP to dUDP (RNR), then to dUTP (NDPK) then to dUMP (dUTPase), then to dTMP (thymidylate synthase). The last reaction requires folate to put the methyl group onto the U to make it a T.
14. Spina bifida (incomplete closing of the neural tube in infants) has been linked to a deficiency of folic acid and a 70% reduction in the disease is realized when folic acid is supplemented in the mother's diet during pregnancy.
- published: 11 Feb 2014
- views: 4189
Part 4 in this series about MSG (E621) will show how to avoid it in grocery stores and restaurants as MSG has many hidden names!
MSG is used in thousands of products, such as snacks, soups, sauces, meats, flavored potato chips, fast food and Chinese food.
http://naturalnews.com/034272_MSG_monosodium_glutamate.html
http://saynotomsg.com/basics_list.php
MSG is also known as Ajinomoto, Accent, vetsin or umami. MSG is 'hidden' in many other names, such as yeast extract, hydrolised protein, natural flavoring, etc.
http://truthinlabeling.org/hiddensources_printable.pdf
http://msgmyth.com/hidden_names_for_msg.html
MSG makes food taste better but it's NOT safe!
http://naturalnews.com/034031_MSG_health_effects.html
The harmful side effects of MSG include headaches, allergies, growth disruptions, hormonal imbalance, learning disorders, ADHD, behavioral problems, autism, muscle pain, nerve pain, heart attacks and irregularities, impaired circulation, skin rashes, retina damage, stomach, intestine and respiration problems, obesity, cancer, etc.
http://msgtruth.org/body.htm
http://naturalnews.com/024438.html
Many problems don't become obvious until puberty. This is caused by poor functioning of the hormones due to exposure to MSG in the first few years of life.
Dr. John Olney discovered in 1969 that MSG caused brain damage and obesity in mice.
http://personalhealthinformationguide.blogspot.com.es/2010/03/msg-causes-rapid-brain-cell-death.html
http://msgtruth.org/obesity.htm
Enormous amounts of flavor enhancers are added to our food. Governmental agencies such as the US Food & Drug Administration insist that MSG is perfectly safe. But research that 'proves' that MSG is safe is financed by the food industry itself...
"My people are destroyed for lack of knowledge."
Hosea 4:6 (KJV)
Avoid MSG and discover how your health will improve dramatically!
http://msgtruth.org/avoid.htm
For more insight on the toxicity of MSG please watch the film 'Sweet Misery' (start watching at 34:00).
http://youtube.com/watch?v=usGh-SRUWBQ
Insightful book about MSG 'Excitotoxins: The Taste That Kills' by Dr. Russell Blaylock, MD.
http://amazon.com/Excitotoxins-The-Taste-That-Kills/dp/0929173252
http://youtube.com/watch?v=tTSvlGniHok
Additives that ALWAYS contain MSG:
gelatin, calcium caseinate, sodium caseinate, monosodium glutamate, hydrolyzed vegetable protein (HVP), textured protein (including TVP), hydrogenated vegetable oil, autolyzed plant protein, monopotassium glutamate, hydrolyzed protein, hydrolyzed plant protein (HPP), hydrolyzed oat flour, corn oil, plant protein extract, sodium caseinate, glutamate, glutamic acid, yeast extract, yeast food or nutrient, autolyzed yeast.
Additives that OFTEN contain MSG:
natural flavors, flavors, flavoring, seasonings, broth, bouillon, malted barley, modified food starch, barley malt, reaction flavors, rice syrup or brown rice syrup, stock, malt extract or flavoring, natural chicken, beef or pork flavoring, maltodextrin, dextrose, dextrates, lipolyzed butter fat, caramel flavoring (coloring), soy protein, soy sauce or extract, soy protein iIsolate or concentrate, corn syrup and corn syrup solids, high fructose corn syrup, citric acid, cornstarch fructose, milk powder, dry milk solids, protein fortified milk, carrageenan, wheat, rice, corn or oat protein, flowing agents, whey protein or whey, anything enriched or vitamin enriched, protein fortified 'anything', annatto, whey protein isolate or concentrate, yeast nutrients, enzyme modified 'anything', spice, pectin, guar and vegetable gums, ultra-pasteurized 'anything', dough conditioners, lecithin, protease, protease enzymes, fermented 'anything', gluten and gluten flour, protein powders (whey, soy, oat, and rice) used in protein bars, shakes and body building drinks, amino acids, wheat/ barley grass powders, artificial flavor.
The names and E-numbers of harmful flavor enhancers:
E620 Glutamic acid
E621 Monosodium glutamate
E622 Monopotassium glutamate
E623 Calcium diglutamate
E624 Monoammonium glutamate
E625 Magnesium diglutamate
E626 Guanylic acid
E627 Disodium guanylate
E628 Dipotassium guanylate
E629 Calcium guanylate
E630 Inosinic acid
E631 Disodium inosinate
E632 Dipotassium inosinate
E633 Calcium inosinate
E634 Calcium 5'-ribonucleotides
E635 Disodium 5'-ribonucleotide
E636 Maltol
E637 Ethylmaltol
Playlist 'The Dangers of MSG (E621)'
http://youtube.com/view_play_list?p=E7C6A9A386BB500E
More information about MSG:
http://msgmyth.com
http://saynotomsg.com
http://truthinlabeling.org
http://msgtruth.org
http://kisswebpage.com/msg
http://feingold.org/Research/msg.html
http://msgtruth.org/related.htm
http://www.advancedhealthplan.com/msgstudy.html
http://science.naturalnews.com
My video playlist 'Dangers in our Food':
http://youtube.com/playlist?list=PLxeNMshhLFQI1ZObMI4zuntcg71ufNBpg
HealthRanger7
http://youtube.com/HealthRanger7
- published: 10 Mar 2008
- views: 64005
Inosinic acid
Inosinic acid or inosine monophosphate (IMP) is a nucleoside monophosphate. Inosinic acid is important in metabolism. It is the ribonucleotide of hypoxanthine and the first nucleotide formed during the synthesis of purine. It is formed by the deamination of adenosine monophosphate, and is hydrolysed from inosine. IMP is an intermediate ribonucleoside monophosphate in purine metabolism. The enzyme deoxyribonucleoside triphosphate pyrophosphohydrolase, encoded by YJR069C in Saccharomyces cerevisiae and containing (d)ITPase and (d)XTPase activities, hydrolyses ITP releasing pyrophosphate and IMP.
Important derivatives of inosinic acid include purine nucleotides found in nucleic acids and adenosine triphosphate, which is used to store chemical energy in muscle and other tissues.
In the food industry, inosinic acid and its salts such as disodium inosinate are used as flavour enhancers.
Inosinate synthesis
The inosinate synthesis is complex, beginning with a 5-phosphoribosyl-1-pyrophosphate (PRPP). In the first step, an amino group given by glutamine is attached at carbon 1 of PRPP. The resulting molecule is 5-phosphoribosylamine, which is highly unstable, with a half-life of 30 seconds at physiologic pH. 5-Phosphoribosylamine gains an amino acid (glycine), becoming glycinamide ribonucleotide (GAR). Then, N10-formyltetrahydrofolate (Tetrahydrofolate) transfers a formyl group to glycinamide ribonucleotide to form formyl glycinamide ribonucleotide (FGAR).
This page contains text from Wikipedia, the Free Encyclopedia -
https://wn.com/Inosinic_acid
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
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0:35Inosinic acid Meaning
Inosinic acid MeaningInosinic acid Meaning
Video shows what inosinic acid means. a nucleotide, inosine phosphate, found in muscle tissue. inosinic acid synonyms: E630 when used as a flavour enhancer. Inosinic acid Meaning. How to pronounce, definition audio dictionary. How to say inosinic acid. Powered by MaryTTS, Wiktionary -
13:04Synthesis of Purine Nucleotides (Easy)
Synthesis of Purine Nucleotides (Easy)Synthesis of Purine Nucleotides (Easy)
Biosynthesis of purines (adenosine and guanine) from ribose-5-phosphate (this occurs in the cytoplasm of every cell, but mostly in the liver). Correction: the ribose-5-phosphate using ATP to the 5-phosphpribosyl-1-pyrophosphate becomes AMP, not ADP like I wrote up. And its guanosine* not guanine monophosphate. Missing step in video but still important - IMP is converted to adenlylosuccinate before being converted to AMP. Not explained in video but still important - Regulation of Purine Synthesis: - AMP and GMP inhibit amido-transferase. - AMP and GMP also inhibit their own formation by feedback inhibition of adenylosuccinate synthetase and IMP dehydrogenase. - The availability of PRPP (phosphoribosyl-1-pyrophosphate) is also a modulatory factor. First I go over the most important steps, then I list every single step in the pathway. -
28:00Rika's TOKYO CUISINE Chicken Breast and Umeboshi Rice - Dining with the Chef
Rika's TOKYO CUISINE Chicken Breast and Umeboshi Rice - Dining with the ChefRika's TOKYO CUISINE Chicken Breast and Umeboshi Rice - Dining with the Chef
In this episode, we'll be making rice with healthy chicken breast and umeboshi pickled plums. We'll be cooking the chicken rare, to help it keep its flavor, with green shiso leaves and a refreshing ume plum sauce. For a side dish, we'll be making egg drop soup, using the water we cooked the chicken in. With the glutamic acid from kombu kelp and the inosinic acid from the chicken, this soup has plenty of umami for a rich, delicious flavor. We'll also be making potato salad with green beans. This simple salad is made by lightly boiling our vegetables, then adding a special sauce made with mayonnaise and wasabi. -
2:02Disodium inosinate
Disodium inosinateDisodium inosinate
Disodium inosinate is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. It is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks. This video is targeted to blind users. Attribution: Article text available under CC-BY-SA Creative Commons image source in video -
49:34#39 Biochemistry Nucleotide Metabolism I Lecture for Kevin Ahern's BB 451/551
#39 Biochemistry Nucleotide Metabolism I Lecture for Kevin Ahern's BB 451/551#39 Biochemistry Nucleotide Metabolism I Lecture for Kevin Ahern's BB 451/551
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern) 2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409 4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1 6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all 7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html 8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB 9. Course materials at http://oregonstate.edu/instruct/bb451 Nucleotide Metabolism 1. Nucleotides consist of a) sugar, b) nitrogenous base, and c) phosphate 2. Nucleosides consist of a a) sugar and b) nitrogenous base 3. The sugars of nucleosides and nucleotides are either ribose (found in ribonucleotides of RNA) or deoxyribose (found in deoxyribonucleotides of DNA). 4. Unless otherwise specified, the term "nucleoside" will be used in this class to indicate either ribonucleosides (contain ribose) or deoxyribonucleosides (contain deoxyribose). 5. The term nucleoside phosphate is equivalent to a nucleotide (nucleoside + phosphate + base = nucleotide). This is true whether it is a monophosphate, diphosphate, or triphosphate. 6. The nitrogenous bases found in nucleotides include adenine (purine), guanine (purine), thymine (pyrimidine), cytosine (pyrimidine), and uracil (pyrimidine). 7. The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism. 8. Ribonucleotides are the building blocks of RNA and deoxyribonucleotides are the building blocks of DNA. 9. Nucleotides and nucleosides are made in cells by 1) salvage pathways or 2) de novo pathways. 10. In salvage pathways, nucleic acids can be broken down to nucleoside monophosphates or individual bases. Monophosphates be rephosphorylated to triphosphates. Alternatively, nucleoside monophosphates can lose a phosphate (becoming nucleosides) or can lose the phosphate and the sugar to become a base. 11. In de novo synthesis of nucleotides, ribonucleotides are synthesized first. Deoxyribonucleotides are made from ribonucleoside diphosphates. Atoms in the ring of pyrimidines come from aspartate and carbamoyl phosphate. 12. The enzyme carbamoyl phosphate synthetase has a catalytic strategy involving channeling of the substrates through the enzyme as catalysis occurs. This is important because some of the intermediates (such as carboxyphosphate and carbamic acid) are very unstable in aqueous solution. 13. The most important regulatory enzyme for the pathway of pyrimidine biosynthesis is ATCase, which plays an important role in balancing the amounts of purines and pyrimidines. The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate. 14. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP. 15. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate. 16. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP. 17. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present. 18. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle. 19. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate). 20. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP. 21. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released. 22. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. Nucleoside diphosphate kinase (NDP kinase or NDPK) converts all nucleoside diphosphates to nucleoside triphosphates. -
0:27Inosinate Meaning
Inosinate Meaning -
1:01極旨！キンキの開き。 Super Yum! Cut-open and dried Channel Rockfish
極旨！キンキの開き。 Super Yum! Cut-open and dried Channel Rockfish極旨！キンキの開き。 Super Yum! Cut-open and dried Channel Rockfish
巨大サイズのキンキの開き。根室の潮風が最高のスパイス！ Huge size of cut-open and dried Channel Rockfish. This is traditional method of food preservation. Moreover, it makes more "Inosinic acid," which is one of the element of "Umami." This is how NemuRock does it baby!! -
47:37Kevin Ahern's Bite-Sized Biochemistry #39 - Nucleotide Metabolism I
Kevin Ahern's Bite-Sized Biochemistry #39 - Nucleotide Metabolism IKevin Ahern's Bite-Sized Biochemistry #39 - Nucleotide Metabolism I
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern) 2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409 4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1 6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all 7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html 8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB 9. Course materials at http://oregonstate.edu/instruct/bb451 Nucleotide Metabolism 1. Nucleotides consist of a) sugar, b) nitrogenous base, and c) phosphate 2. Nucleosides consist of a a) sugar and b) nitrogenous base 3. The sugars of nucleosides and nucleotides are either ribose (found in ribonucleotides of RNA) or deoxyribose (found in deoxyribonucleotides of DNA). 4. Unless otherwise specified, the term "nucleoside" will be used in this class to indicate either ribonucleosides (contain ribose) or deoxyribonucleosides (contain deoxyribose). 5. The term nucleoside phosphate is equivalent to a nucleotide (nucleoside + phosphate + base = nucleotide). This is true whether it is a monophosphate, diphosphate, or triphosphate. 6. The nitrogenous bases found in nucleotides include adenine (purine), guanine (purine), thymine (pyrimidine), cytosine (pyrimidine), and uracil (pyrimidine). 7. The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism. 8. Ribonucleotides are the building blocks of RNA and deoxyribonucleotides are the building blocks of DNA. 9. Nucleotides and nucleosides are made in cells by 1) salvage pathways or 2) de novo pathways. 10. In salvage pathways, nucleic acids can be broken down to nucleoside monophosphates or individual bases. Monophosphates be rephosphorylated to triphosphates. Alternatively, nucleoside monophosphates can lose a phosphate (becoming nucleosides) or can lose the phosphate and the sugar to become a base. 11. In de novo synthesis of nucleotides, ribonucleotides are synthesized first. Deoxyribonucleotides are made from ribonucleoside diphosphates. Atoms in the ring of pyrimidines come from aspartate and carbamoyl phosphate. 12. The enzyme carbamoyl phosphate synthetase has a catalytic strategy involving channeling of the substrates through the enzyme as catalysis occurs. This is important because some of the intermediates (such as carboxyphosphate and carbamic acid) are very unstable in aqueous solution. 13. The most important regulatory enzyme for the pathway of pyrimidine biosynthesis is ATCase, which plays an important role in balancing the amounts of purines and pyrimidines. The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate. 14. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP. 15. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate. 16. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP. 17. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present. 18. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle. 19. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate). 20. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP. 21. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released. 22. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. Nucleoside diphosphate kinase (NDP kinase or NDPK) converts all nucleoside diphosphates to nucleoside triphosphates. -
49:2139. Kevin Ahern's Biochemistry - Nucleotide Metabolism II
39. Kevin Ahern's Biochemistry - Nucleotide Metabolism II39. Kevin Ahern's Biochemistry - Nucleotide Metabolism II
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern) 2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409 4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 5. Lecturio videos for medical students - https://www.lecturio.com/medical-courses/biochemistry.course 6. Course video channel at http://www.youtube.com/user/oharow/videos?view=1 7. Check out all of my free workshops at http://oregonstate.edu/dept/biochem/ahern/123.html 8. Check out my Metabolic Melodies at http://www.davincipress.com/ 9. My courses can be taken for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB 10. Course materials at http://oregonstate.edu/instruct/bb451 Highlights - Nucleotide Metabolism II 1. The most important regulatory enzyme for the entire pathway of pyrimidine biosynthesis is aspartate transcarbamoylase (ATCase), which plays an important role in balancing the amounts of purines and pyrimidines and also measuring the amount of energy available (via the amount of ATP present). The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate and is allosterically activated by ATP and allosterically inactivated by CTP. 2. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP. 3. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate, but all diphosphates (purines, pyrimidines, and all deoxyribonucleoside diphosphates) are converted to triphosphates by NDPK. 4. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP, thus providing a balance between the amount of CTP and UTP. 5. De novo synthesis of purines uses atoms from aspartate, glycine, glutamine, carbon dioxide, and tetrahyrdofolate derivatives to make the purine ring. 6. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present. This enzyme helps to control purine production and also slows purine production when one nucleotide gets to be in too high of a concentration. 7. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle. 8. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate). 9. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP. Thus, the critical balance of these two nucleotides is maintained using this scheme. 10. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released. 11. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. These enzymes include AMP kinase (also called adenylate kinase) and GMP kinase (also called guanylate kinase), which convert nucleoside monophosphates to nucleoside diphosphates, and nucleoside diphosphate kinase (NDP kinase or NDPK), which converts all nucleoside diphosphates to nucleoside triphosphates. 12. Deoxyribonucleotides are made starting with ribonucleotide reductase (RNR). It catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates (for example, ADP to dADP). RNR works on all of the ribonucleoside diphosphates. NDPK converts all of the nucleoside diphosphates to nucleoside triphosphates using energy from other triphosphates. 13. The pathway to making thymidine nucleotides is more complicated. It goes from UDP to dUDP (RNR), then to dUTP (NDPK) then to dUMP (dUTPase), then to dTMP (thymidylate synthase). The last reaction requires folate to put the methyl group onto the U to make it a T. 14. Spina bifida (incomplete closing of the neural tube in infants) has been linked to a deficiency of folic acid and a 70% reduction in the disease is realized when folic acid is supplemented in the mother's diet during pregnancy. -
7:11The Dangers of MSG - Part 4 'Avoiding the MSG Threat' (Flavor Enhancers E621 side effects)
The Dangers of MSG - Part 4 'Avoiding the MSG Threat' (Flavor Enhancers E621 side effects)The Dangers of MSG - Part 4 'Avoiding the MSG Threat' (Flavor Enhancers E621 side effects)
Part 4 in this series about MSG (E621) will show how to avoid it in grocery stores and restaurants as MSG has many hidden names! MSG is used in thousands of products, such as snacks, soups, sauces, meats, flavored potato chips, fast food and Chinese food. http://naturalnews.com/034272_MSG_monosodium_glutamate.html http://saynotomsg.com/basics_list.php MSG is also known as Ajinomoto, Accent, vetsin or umami. MSG is 'hidden' in many other names, such as yeast extract, hydrolised protein, natural flavoring, etc. http://truthinlabeling.org/hiddensources_printable.pdf http://msgmyth.com/hidden_names_for_msg.html MSG makes food taste better but it's NOT safe! http://naturalnews.com/034031_MSG_health_effects.html The harmful side effects of MSG include headaches, allergies, growth disruptions, hormonal imbalance, learning disorders, ADHD, behavioral problems, autism, muscle pain, nerve pain, heart attacks and irregularities, impaired circulation, skin rashes, retina damage, stomach, intestine and respiration problems, obesity, cancer, etc. http://msgtruth.org/body.htm http://naturalnews.com/024438.html Many problems don't become obvious until puberty. This is caused by poor functioning of the hormones due to exposure to MSG in the first few years of life. Dr. John Olney discovered in 1969 that MSG caused brain damage and obesity in mice. http://personalhealthinformationguide.blogspot.com.es/2010/03/msg-causes-rapid-brain-cell-death.html http://msgtruth.org/obesity.htm Enormous amounts of flavor enhancers are added to our food. Governmental agencies such as the US Food & Drug Administration insist that MSG is perfectly safe. But research that 'proves' that MSG is safe is financed by the food industry itself... "My people are destroyed for lack of knowledge." Hosea 4:6 (KJV) Avoid MSG and discover how your health will improve dramatically! http://msgtruth.org/avoid.htm For more insight on the toxicity of MSG please watch the film 'Sweet Misery' (start watching at 34:00). http://youtube.com/watch?v=usGh-SRUWBQ Insightful book about MSG 'Excitotoxins: The Taste That Kills' by Dr. Russell Blaylock, MD. http://amazon.com/Excitotoxins-The-Taste-That-Kills/dp/0929173252 http://youtube.com/watch?v=tTSvlGniHok Additives that ALWAYS contain MSG: gelatin, calcium caseinate, sodium caseinate, monosodium glutamate, hydrolyzed vegetable protein (HVP), textured protein (including TVP), hydrogenated vegetable oil, autolyzed plant protein, monopotassium glutamate, hydrolyzed protein, hydrolyzed plant protein (HPP), hydrolyzed oat flour, corn oil, plant protein extract, sodium caseinate, glutamate, glutamic acid, yeast extract, yeast food or nutrient, autolyzed yeast. Additives that OFTEN contain MSG: natural flavors, flavors, flavoring, seasonings, broth, bouillon, malted barley, modified food starch, barley malt, reaction flavors, rice syrup or brown rice syrup, stock, malt extract or flavoring, natural chicken, beef or pork flavoring, maltodextrin, dextrose, dextrates, lipolyzed butter fat, caramel flavoring (coloring), soy protein, soy sauce or extract, soy protein iIsolate or concentrate, corn syrup and corn syrup solids, high fructose corn syrup, citric acid, cornstarch fructose, milk powder, dry milk solids, protein fortified milk, carrageenan, wheat, rice, corn or oat protein, flowing agents, whey protein or whey, anything enriched or vitamin enriched, protein fortified 'anything', annatto, whey protein isolate or concentrate, yeast nutrients, enzyme modified 'anything', spice, pectin, guar and vegetable gums, ultra-pasteurized 'anything', dough conditioners, lecithin, protease, protease enzymes, fermented 'anything', gluten and gluten flour, protein powders (whey, soy, oat, and rice) used in protein bars, shakes and body building drinks, amino acids, wheat/ barley grass powders, artificial flavor. The names and E-numbers of harmful flavor enhancers: E620 Glutamic acid E621 Monosodium glutamate E622 Monopotassium glutamate E623 Calcium diglutamate E624 Monoammonium glutamate E625 Magnesium diglutamate E626 Guanylic acid E627 Disodium guanylate E628 Dipotassium guanylate E629 Calcium guanylate E630 Inosinic acid E631 Disodium inosinate E632 Dipotassium inosinate E633 Calcium inosinate E634 Calcium 5'-ribonucleotides E635 Disodium 5'-ribonucleotide E636 Maltol E637 Ethylmaltol Playlist 'The Dangers of MSG (E621)' http://youtube.com/view_play_list?p=E7C6A9A386BB500E More information about MSG: http://msgmyth.com http://saynotomsg.com http://truthinlabeling.org http://msgtruth.org http://kisswebpage.com/msg http://feingold.org/Research/msg.html http://msgtruth.org/related.htm http://www.advancedhealthplan.com/msgstudy.html http://science.naturalnews.com My video playlist 'Dangers in our Food': http://youtube.com/playlist?list=PLxeNMshhLFQI1ZObMI4zuntcg71ufNBpg HealthRanger7 http://youtube.com/HealthRanger7
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Inosinic acid Meaning
Video shows what inosinic acid means. a nucleotide, inosine phosphate, found in muscle tissue. inosinic acid synonyms: E630 when used as a flavour enhancer. Inosinic acid Meaning. How to pronounce, definition audio dictionary. How to say inosinic acid. Powered by MaryTTS, Wiktionary
published: 26 Apr 2015 -
Synthesis of Purine Nucleotides (Easy)
Biosynthesis of purines (adenosine and guanine) from ribose-5-phosphate (this occurs in the cytoplasm of every cell, but mostly in the liver). Correction: the ribose-5-phosphate using ATP to the 5-phosphpribosyl-1-pyrophosphate becomes AMP, not ADP like I wrote up. And its guanosine* not guanine monophosphate. Missing step in video but still important - IMP is converted to adenlylosuccinate before being converted to AMP. Not explained in video but still important - Regulation of Purine Synthesis: - AMP and GMP inhibit amido-transferase. - AMP and GMP also inhibit their own formation by feedback inhibition of adenylosuccinate synthetase and IMP dehydrogenase. - The availability of PRPP (phosphoribosyl-1-pyrophosphate) is also a modulatory factor. First I go over the most important steps...
published: 30 Apr 2016 -
Rika's TOKYO CUISINE Chicken Breast and Umeboshi Rice - Dining with the Chef
In this episode, we'll be making rice with healthy chicken breast and umeboshi pickled plums. We'll be cooking the chicken rare, to help it keep its flavor, with green shiso leaves and a refreshing ume plum sauce. For a side dish, we'll be making egg drop soup, using the water we cooked the chicken in. With the glutamic acid from kombu kelp and the inosinic acid from the chicken, this soup has plenty of umami for a rich, delicious flavor. We'll also be making potato salad with green beans. This simple salad is made by lightly boiling our vegetables, then adding a special sauce made with mayonnaise and wasabi.
published: 11 Oct 2016 -
Disodium inosinate
Disodium inosinate is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. It is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks. This video is targeted to blind users. Attribution: Article text available under CC-BY-SA Creative Commons image source in video
published: 22 Dec 2015 -
#39 Biochemistry Nucleotide Metabolism I Lecture for Kevin Ahern's BB 451/551
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern) 2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409 4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1 6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all 7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html 8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu...
published: 10 Feb 2012 -
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極旨！キンキの開き。 Super Yum! Cut-open and dried Channel Rockfish
巨大サイズのキンキの開き。根室の潮風が最高のスパイス！ Huge size of cut-open and dried Channel Rockfish. This is traditional method of food preservation. Moreover, it makes more "Inosinic acid," which is one of the element of "Umami." This is how NemuRock does it baby!!
published: 13 May 2016 -
Kevin Ahern's Bite-Sized Biochemistry #39 - Nucleotide Metabolism I
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern) 2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409 4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1 6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all 7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html 8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu...
published: 03 Aug 2011 -
39. Kevin Ahern's Biochemistry - Nucleotide Metabolism II
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern) 2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409 4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy 5. Lecturio videos for medical students - https://www.lecturio.com/medical-courses/biochemistry.course 6. Course video channel at http://www.youtube.com/user/oharow/videos?view=1 7. Check out all of my free workshops at http://oregonstate.edu/dept/biochem/ahern/123.html 8. Check out my Metabolic Melodies at http://www.davincipress.com/ 9. My courses can be taken for credit (wherever you live) via OSU's e...
published: 11 Feb 2014 -
The Dangers of MSG - Part 4 'Avoiding the MSG Threat' (Flavor Enhancers E621 side effects)
Part 4 in this series about MSG (E621) will show how to avoid it in grocery stores and restaurants as MSG has many hidden names! MSG is used in thousands of products, such as snacks, soups, sauces, meats, flavored potato chips, fast food and Chinese food. http://naturalnews.com/034272_MSG_monosodium_glutamate.html http://saynotomsg.com/basics_list.php MSG is also known as Ajinomoto, Accent, vetsin or umami. MSG is 'hidden' in many other names, such as yeast extract, hydrolised protein, natural flavoring, etc. http://truthinlabeling.org/hiddensources_printable.pdf http://msgmyth.com/hidden_names_for_msg.html MSG makes food taste better but it's NOT safe! http://naturalnews.com/034031_MSG_health_effects.html The harmful side effects of MSG include headaches, allergies, growth disruption...
published: 10 Mar 2008
Inosinic acid Meaning
- Order: Reorder
- Duration: 0:35
- Updated: 26 Apr 2015
- views: 30
Video shows what inosinic acid means. a nucleotide, inosine phosphate, found in muscle tissue. inosinic acid synonyms: E630 when used as a flavour enhancer. In...
Video shows what inosinic acid means. a nucleotide, inosine phosphate, found in muscle tissue. inosinic acid synonyms: E630 when used as a flavour enhancer. Inosinic acid Meaning. How to pronounce, definition audio dictionary. How to say inosinic acid. Powered by MaryTTS, Wiktionary
wn.com/Inosinic Acid Meaning
Video shows what inosinic acid means. a nucleotide, inosine phosphate, found in muscle tissue. inosinic acid synonyms: E630 when used as a flavour enhancer. Inosinic acid Meaning. How to pronounce, definition audio dictionary. How to say inosinic acid. Powered by MaryTTS, Wiktionary
- published: 26 Apr 2015
- views: 30
Synthesis of Purine Nucleotides (Easy)
- Order: Reorder
- Duration: 13:04
- Updated: 30 Apr 2016
- views: 570
Biosynthesis of purines (adenosine and guanine) from ribose-5-phosphate (this occurs in the cytoplasm of every cell, but mostly in the liver).
Correction: the ...
Biosynthesis of purines (adenosine and guanine) from ribose-5-phosphate (this occurs in the cytoplasm of every cell, but mostly in the liver).
Correction: the ribose-5-phosphate using ATP to the 5-phosphpribosyl-1-pyrophosphate becomes AMP, not ADP like I wrote up. And its guanosine* not guanine monophosphate. Missing step in video but still important - IMP is converted to adenlylosuccinate before being converted to AMP.
Not explained in video but still important - Regulation of Purine Synthesis:
- AMP and GMP inhibit amido-transferase.
- AMP and GMP also inhibit their own formation by feedback inhibition of adenylosuccinate synthetase and IMP dehydrogenase.
- The availability of PRPP (phosphoribosyl-1-pyrophosphate) is also a modulatory factor.
First I go over the most important steps, then I list every single step in the pathway.
wn.com/Synthesis Of Purine Nucleotides (Easy)
Biosynthesis of purines (adenosine and guanine) from ribose-5-phosphate (this occurs in the cytoplasm of every cell, but mostly in the liver).
Correction: the ribose-5-phosphate using ATP to the 5-phosphpribosyl-1-pyrophosphate becomes AMP, not ADP like I wrote up. And its guanosine* not guanine monophosphate. Missing step in video but still important - IMP is converted to adenlylosuccinate before being converted to AMP.
Not explained in video but still important - Regulation of Purine Synthesis:
- AMP and GMP inhibit amido-transferase.
- AMP and GMP also inhibit their own formation by feedback inhibition of adenylosuccinate synthetase and IMP dehydrogenase.
- The availability of PRPP (phosphoribosyl-1-pyrophosphate) is also a modulatory factor.
First I go over the most important steps, then I list every single step in the pathway.
- published: 30 Apr 2016
- views: 570
Rika's TOKYO CUISINE Chicken Breast and Umeboshi Rice - Dining with the Chef
- Order: Reorder
- Duration: 28:00
- Updated: 11 Oct 2016
- views: 16
In this episode, we'll be making rice with healthy chicken breast and umeboshi pickled plums. We'll be cooking the chicken rare, to help it keep its flavor, wit...
In this episode, we'll be making rice with healthy chicken breast and umeboshi pickled plums. We'll be cooking the chicken rare, to help it keep its flavor, with green shiso leaves and a refreshing ume plum sauce. For a side dish, we'll be making egg drop soup, using the water we cooked the chicken in. With the glutamic acid from kombu kelp and the inosinic acid from the chicken, this soup has plenty of umami for a rich, delicious flavor. We'll also be making potato salad with green beans. This simple salad is made by lightly boiling our vegetables, then adding a special sauce made with mayonnaise and wasabi.
wn.com/Rika's Tokyo Cuisine Chicken Breast And Umeboshi Rice Dining With The Chef
In this episode, we'll be making rice with healthy chicken breast and umeboshi pickled plums. We'll be cooking the chicken rare, to help it keep its flavor, with green shiso leaves and a refreshing ume plum sauce. For a side dish, we'll be making egg drop soup, using the water we cooked the chicken in. With the glutamic acid from kombu kelp and the inosinic acid from the chicken, this soup has plenty of umami for a rich, delicious flavor. We'll also be making potato salad with green beans. This simple salad is made by lightly boiling our vegetables, then adding a special sauce made with mayonnaise and wasabi.
- published: 11 Oct 2016
- views: 16
Disodium inosinate
- Order: Reorder
- Duration: 2:02
- Updated: 22 Dec 2015
- views: 104
Disodium inosinate is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. It is used as a food additive and often found in instant nood...
Disodium inosinate is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. It is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks.
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
wn.com/Disodium Inosinate
Disodium inosinate is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P. It is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks.
This video is targeted to blind users.
Attribution:
Article text available under CC-BY-SA
Creative Commons image source in video
- published: 22 Dec 2015
- views: 104
#39 Biochemistry Nucleotide Metabolism I Lecture for Kevin Ahern's BB 451/551
- Order: Reorder
- Duration: 49:34
- Updated: 10 Feb 2012
- views: 10480
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.ed...
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409
4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1
6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all
7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html
8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB
9. Course materials at http://oregonstate.edu/instruct/bb451
Nucleotide Metabolism
1. Nucleotides consist of a) sugar, b) nitrogenous base, and c) phosphate
2. Nucleosides consist of a a) sugar and b) nitrogenous base
3. The sugars of nucleosides and nucleotides are either ribose (found in ribonucleotides of RNA) or deoxyribose (found in deoxyribonucleotides of DNA).
4. Unless otherwise specified, the term "nucleoside" will be used in this class to indicate either ribonucleosides (contain ribose) or deoxyribonucleosides (contain deoxyribose).
5. The term nucleoside phosphate is equivalent to a nucleotide (nucleoside + phosphate + base = nucleotide). This is true whether it is a monophosphate, diphosphate, or triphosphate.
6. The nitrogenous bases found in nucleotides include adenine (purine), guanine (purine), thymine (pyrimidine), cytosine (pyrimidine), and uracil (pyrimidine).
7. The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism.
8. Ribonucleotides are the building blocks of RNA and deoxyribonucleotides are the building blocks of DNA.
9. Nucleotides and nucleosides are made in cells by 1) salvage pathways or 2) de novo pathways.
10. In salvage pathways, nucleic acids can be broken down to nucleoside monophosphates or individual bases. Monophosphates be rephosphorylated to triphosphates. Alternatively, nucleoside monophosphates can lose a phosphate (becoming nucleosides) or can lose the phosphate and the sugar to become a base.
11. In de novo synthesis of nucleotides, ribonucleotides are synthesized first. Deoxyribonucleotides are made from ribonucleoside diphosphates. Atoms in the ring of pyrimidines come from aspartate and carbamoyl phosphate.
12. The enzyme carbamoyl phosphate synthetase has a catalytic strategy involving channeling of the substrates through the enzyme as catalysis occurs. This is important because some of the intermediates (such as carboxyphosphate and carbamic acid) are very unstable in aqueous solution.
13. The most important regulatory enzyme for the pathway of pyrimidine biosynthesis is ATCase, which plays an important role in balancing the amounts of purines and pyrimidines. The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate.
14. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP.
15. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate.
16. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP.
17. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present.
18. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle.
19. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate).
20. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP.
21. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released.
22. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. Nucleoside diphosphate kinase (NDP kinase or NDPK) converts all nucleoside diphosphates to nucleoside triphosphates.
wn.com/39 Biochemistry Nucleotide Metabolism I Lecture For Kevin Ahern's Bb 451 551
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409
4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1
6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all
7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html
8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB
9. Course materials at http://oregonstate.edu/instruct/bb451
Nucleotide Metabolism
1. Nucleotides consist of a) sugar, b) nitrogenous base, and c) phosphate
2. Nucleosides consist of a a) sugar and b) nitrogenous base
3. The sugars of nucleosides and nucleotides are either ribose (found in ribonucleotides of RNA) or deoxyribose (found in deoxyribonucleotides of DNA).
4. Unless otherwise specified, the term "nucleoside" will be used in this class to indicate either ribonucleosides (contain ribose) or deoxyribonucleosides (contain deoxyribose).
5. The term nucleoside phosphate is equivalent to a nucleotide (nucleoside + phosphate + base = nucleotide). This is true whether it is a monophosphate, diphosphate, or triphosphate.
6. The nitrogenous bases found in nucleotides include adenine (purine), guanine (purine), thymine (pyrimidine), cytosine (pyrimidine), and uracil (pyrimidine).
7. The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism.
8. Ribonucleotides are the building blocks of RNA and deoxyribonucleotides are the building blocks of DNA.
9. Nucleotides and nucleosides are made in cells by 1) salvage pathways or 2) de novo pathways.
10. In salvage pathways, nucleic acids can be broken down to nucleoside monophosphates or individual bases. Monophosphates be rephosphorylated to triphosphates. Alternatively, nucleoside monophosphates can lose a phosphate (becoming nucleosides) or can lose the phosphate and the sugar to become a base.
11. In de novo synthesis of nucleotides, ribonucleotides are synthesized first. Deoxyribonucleotides are made from ribonucleoside diphosphates. Atoms in the ring of pyrimidines come from aspartate and carbamoyl phosphate.
12. The enzyme carbamoyl phosphate synthetase has a catalytic strategy involving channeling of the substrates through the enzyme as catalysis occurs. This is important because some of the intermediates (such as carboxyphosphate and carbamic acid) are very unstable in aqueous solution.
13. The most important regulatory enzyme for the pathway of pyrimidine biosynthesis is ATCase, which plays an important role in balancing the amounts of purines and pyrimidines. The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate.
14. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP.
15. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate.
16. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP.
17. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present.
18. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle.
19. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate).
20. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP.
21. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released.
22. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. Nucleoside diphosphate kinase (NDP kinase or NDPK) converts all nucleoside diphosphates to nucleoside triphosphates.
- published: 10 Feb 2012
- views: 10480
Inosinate Meaning
- Order: Reorder
- Duration: 0:27
- Updated: 26 Apr 2015
- views: 42
Video shows what inosinate means. any salt or ester of inosinic acid, the salts are used as flavour enhancers. Inosinate Meaning. How to pronounce, definition ...
Video shows what inosinate means. any salt or ester of inosinic acid, the salts are used as flavour enhancers. Inosinate Meaning. How to pronounce, definition audio dictionary. How to say inosinate. Powered by MaryTTS, Wiktionary
wn.com/Inosinate Meaning
極旨！キンキの開き。 Super Yum! Cut-open and dried Channel Rockfish
- Order: Reorder
- Duration: 1:01
- Updated: 13 May 2016
- views: 40
巨大サイズのキンキの開き。根室の潮風が最高のスパイス！
Huge size of cut-open and dried Channel Rockfish.
This is traditional method of food preservation. Moreover, it makes more "Inosini...
巨大サイズのキンキの開き。根室の潮風が最高のスパイス！
Huge size of cut-open and dried Channel Rockfish.
This is traditional method of food preservation. Moreover, it makes more "Inosinic acid," which is one of the element of "Umami."
This is how NemuRock does it baby!!
wn.com/極旨！キンキの開き。 Super Yum Cut Open And Dried Channel Rockfish
巨大サイズのキンキの開き。根室の潮風が最高のスパイス！
Huge size of cut-open and dried Channel Rockfish.
This is traditional method of food preservation. Moreover, it makes more "Inosinic acid," which is one of the element of "Umami."
This is how NemuRock does it baby!!
- published: 13 May 2016
- views: 40
Kevin Ahern's Bite-Sized Biochemistry #39 - Nucleotide Metabolism I
- Order: Reorder
- Duration: 47:37
- Updated: 03 Aug 2011
- views: 6399
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.ed...
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409
4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1
6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all
7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html
8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB
9. Course materials at http://oregonstate.edu/instruct/bb451
Nucleotide Metabolism
1. Nucleotides consist of a) sugar, b) nitrogenous base, and c) phosphate
2. Nucleosides consist of a a) sugar and b) nitrogenous base
3. The sugars of nucleosides and nucleotides are either ribose (found in ribonucleotides of RNA) or deoxyribose (found in deoxyribonucleotides of DNA).
4. Unless otherwise specified, the term "nucleoside" will be used in this class to indicate either ribonucleosides (contain ribose) or deoxyribonucleosides (contain deoxyribose).
5. The term nucleoside phosphate is equivalent to a nucleotide (nucleoside + phosphate + base = nucleotide). This is true whether it is a monophosphate, diphosphate, or triphosphate.
6. The nitrogenous bases found in nucleotides include adenine (purine), guanine (purine), thymine (pyrimidine), cytosine (pyrimidine), and uracil (pyrimidine).
7. The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism.
8. Ribonucleotides are the building blocks of RNA and deoxyribonucleotides are the building blocks of DNA.
9. Nucleotides and nucleosides are made in cells by 1) salvage pathways or 2) de novo pathways.
10. In salvage pathways, nucleic acids can be broken down to nucleoside monophosphates or individual bases. Monophosphates be rephosphorylated to triphosphates. Alternatively, nucleoside monophosphates can lose a phosphate (becoming nucleosides) or can lose the phosphate and the sugar to become a base.
11. In de novo synthesis of nucleotides, ribonucleotides are synthesized first. Deoxyribonucleotides are made from ribonucleoside diphosphates. Atoms in the ring of pyrimidines come from aspartate and carbamoyl phosphate.
12. The enzyme carbamoyl phosphate synthetase has a catalytic strategy involving channeling of the substrates through the enzyme as catalysis occurs. This is important because some of the intermediates (such as carboxyphosphate and carbamic acid) are very unstable in aqueous solution.
13. The most important regulatory enzyme for the pathway of pyrimidine biosynthesis is ATCase, which plays an important role in balancing the amounts of purines and pyrimidines. The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate.
14. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP.
15. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate.
16. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP.
17. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present.
18. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle.
19. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate).
20. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP.
21. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released.
22. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. Nucleoside diphosphate kinase (NDP kinase or NDPK) converts all nucleoside diphosphates to nucleoside triphosphates.
wn.com/Kevin Ahern's Bite Sized Biochemistry 39 Nucleotide Metabolism I
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409
4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
5. Course video channel at http://www.youtube.com/user/oharow/videos?view=1
6. Check out all of my free workshops at http://www.youtube.com/playlist?list=PLlnFrNM93wqyTiCLZKehU1Tp8rNmnOWYB&feature;=view_all
7. Check out my Metabolic Melodies at http://www.davincipress.com/metabmelodies.html
8. Take my courses for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB
9. Course materials at http://oregonstate.edu/instruct/bb451
Nucleotide Metabolism
1. Nucleotides consist of a) sugar, b) nitrogenous base, and c) phosphate
2. Nucleosides consist of a a) sugar and b) nitrogenous base
3. The sugars of nucleosides and nucleotides are either ribose (found in ribonucleotides of RNA) or deoxyribose (found in deoxyribonucleotides of DNA).
4. Unless otherwise specified, the term "nucleoside" will be used in this class to indicate either ribonucleosides (contain ribose) or deoxyribonucleosides (contain deoxyribose).
5. The term nucleoside phosphate is equivalent to a nucleotide (nucleoside + phosphate + base = nucleotide). This is true whether it is a monophosphate, diphosphate, or triphosphate.
6. The nitrogenous bases found in nucleotides include adenine (purine), guanine (purine), thymine (pyrimidine), cytosine (pyrimidine), and uracil (pyrimidine).
7. The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism.
8. Ribonucleotides are the building blocks of RNA and deoxyribonucleotides are the building blocks of DNA.
9. Nucleotides and nucleosides are made in cells by 1) salvage pathways or 2) de novo pathways.
10. In salvage pathways, nucleic acids can be broken down to nucleoside monophosphates or individual bases. Monophosphates be rephosphorylated to triphosphates. Alternatively, nucleoside monophosphates can lose a phosphate (becoming nucleosides) or can lose the phosphate and the sugar to become a base.
11. In de novo synthesis of nucleotides, ribonucleotides are synthesized first. Deoxyribonucleotides are made from ribonucleoside diphosphates. Atoms in the ring of pyrimidines come from aspartate and carbamoyl phosphate.
12. The enzyme carbamoyl phosphate synthetase has a catalytic strategy involving channeling of the substrates through the enzyme as catalysis occurs. This is important because some of the intermediates (such as carboxyphosphate and carbamic acid) are very unstable in aqueous solution.
13. The most important regulatory enzyme for the pathway of pyrimidine biosynthesis is ATCase, which plays an important role in balancing the amounts of purines and pyrimidines. The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate.
14. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP.
15. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate.
16. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP.
17. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present.
18. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle.
19. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate).
20. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP.
21. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released.
22. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. Nucleoside diphosphate kinase (NDP kinase or NDPK) converts all nucleoside diphosphates to nucleoside triphosphates.
- published: 03 Aug 2011
- views: 6399
39. Kevin Ahern's Biochemistry - Nucleotide Metabolism II
- Order: Reorder
- Duration: 49:21
- Updated: 11 Feb 2014
- views: 4189
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.ed...
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409
4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
5. Lecturio videos for medical students - https://www.lecturio.com/medical-courses/biochemistry.course
6. Course video channel at http://www.youtube.com/user/oharow/videos?view=1
7. Check out all of my free workshops at http://oregonstate.edu/dept/biochem/ahern/123.html
8. Check out my Metabolic Melodies at http://www.davincipress.com/
9. My courses can be taken for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB
10. Course materials at http://oregonstate.edu/instruct/bb451
Highlights - Nucleotide Metabolism II
1. The most important regulatory enzyme for the entire pathway of pyrimidine biosynthesis is aspartate transcarbamoylase (ATCase), which plays an important role in balancing the amounts of purines and pyrimidines and also measuring the amount of energy available (via the amount of ATP present). The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate and is allosterically activated by ATP and allosterically inactivated by CTP.
2. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP.
3. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate, but all diphosphates (purines, pyrimidines, and all deoxyribonucleoside diphosphates) are converted to triphosphates by NDPK.
4. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP, thus providing a balance between the amount of CTP and UTP.
5. De novo synthesis of purines uses atoms from aspartate, glycine, glutamine, carbon dioxide, and tetrahyrdofolate derivatives to make the purine ring.
6. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present. This enzyme helps to control purine production and also slows purine production when one nucleotide gets to be in too high of a concentration.
7. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle.
8. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate).
9. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP. Thus, the critical balance of these two nucleotides is maintained using this scheme.
10. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released.
11. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. These enzymes include AMP kinase (also called adenylate kinase) and GMP kinase (also called guanylate kinase), which convert nucleoside monophosphates to nucleoside diphosphates, and nucleoside diphosphate kinase (NDP kinase or NDPK), which converts all nucleoside diphosphates to nucleoside triphosphates.
12. Deoxyribonucleotides are made starting with ribonucleotide reductase (RNR). It catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates (for example, ADP to dADP). RNR works on all of the ribonucleoside diphosphates. NDPK converts all of the nucleoside diphosphates to nucleoside triphosphates using energy from other triphosphates.
13. The pathway to making thymidine nucleotides is more complicated. It goes from UDP to dUDP (RNR), then to dUTP (NDPK) then to dUMP (dUTPase), then to dTMP (thymidylate synthase). The last reaction requires folate to put the methyl group onto the U to make it a T.
14. Spina bifida (incomplete closing of the neural tube in infants) has been linked to a deficiency of folic acid and a 70% reduction in the disease is realized when folic acid is supplemented in the mother's diet during pregnancy.
wn.com/39. Kevin Ahern's Biochemistry Nucleotide Metabolism Ii
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Download my free biochemistry book at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
3. Take my free iTunes U course at https://itunes.apple.com/us/course/biochemistry/id556410409
4. Check out my free book for pre-meds at http://biochem.science.oregonstate.edu/biochemistry-free-and-easy
5. Lecturio videos for medical students - https://www.lecturio.com/medical-courses/biochemistry.course
6. Course video channel at http://www.youtube.com/user/oharow/videos?view=1
7. Check out all of my free workshops at http://oregonstate.edu/dept/biochem/ahern/123.html
8. Check out my Metabolic Melodies at http://www.davincipress.com/
9. My courses can be taken for credit (wherever you live) via OSU's ecampus. For details, see http://ecampus.oregonstate.edu/soc/ecatalog/ecourselist.htm?termcode=all&subject;=BB
10. Course materials at http://oregonstate.edu/instruct/bb451
Highlights - Nucleotide Metabolism II
1. The most important regulatory enzyme for the entire pathway of pyrimidine biosynthesis is aspartate transcarbamoylase (ATCase), which plays an important role in balancing the amounts of purines and pyrimidines and also measuring the amount of energy available (via the amount of ATP present). The enzyme catalyzes the linkage of aspartate to carbamoyl phosphate and is allosterically activated by ATP and allosterically inactivated by CTP.
2. The first pyrimidine nucleotide made in the de novo pyrimidine pathway is UMP.
3. UMP is phosphorylated to UDP (by uridine monophosphate kinase) and then to UTP (by nucleoside diphosphokinase = NDPK) before conversion to CTP. Each nucleoside monophosphate has a specific kinase to convert it to the diphosphate, but all diphosphates (purines, pyrimidines, and all deoxyribonucleoside diphosphates) are converted to triphosphates by NDPK.
4. Conversion of UTP to CTP is catalyzed by the enzyme CTP synthase and it is inhibited by CTP, thus providing a balance between the amount of CTP and UTP.
5. De novo synthesis of purines uses atoms from aspartate, glycine, glutamine, carbon dioxide, and tetrahyrdofolate derivatives to make the purine ring.
6. The most important regulatory enzyme for the first part of purine biosynthesis is PRPP amidotransferase. It is inhibited fully by AMP and GMP, but is only partly inhibited (is still partly active) when only one of these molecules is present. This enzyme helps to control purine production and also slows purine production when one nucleotide gets to be in too high of a concentration.
7. In the process of making IMP, fumarate is released, thereby connecting purine biosynthesis to the citric acid cycle.
8. The first purine-like intermediate in de novo purine biosynthesis is inosinic acid (or IMP), which has the purine-like base hypoxanthine linked to ribose (and ribose is linked to phosphate).
9. IMP can be converted to AMP or GMP. The pathway by which IMP leads to GMP is inhibited by GMP and uses energy from ATP, whereas the pathway where IMP is converted to AMP is inhibited by AMP and uses energy from GTP. Thus, the critical balance of these two nucleotides is maintained using this scheme.
10. The pathway to GMP involves oxidation, whereas the pathway that leads to AMP uses aspartic acid to donate an amine and fumarate is again released.
11. Nucleoside monophosphates from de novo synthesis can be converted by kinases to nucleoside diphosphates and nucleoside triphosphates. These enzymes include AMP kinase (also called adenylate kinase) and GMP kinase (also called guanylate kinase), which convert nucleoside monophosphates to nucleoside diphosphates, and nucleoside diphosphate kinase (NDP kinase or NDPK), which converts all nucleoside diphosphates to nucleoside triphosphates.
12. Deoxyribonucleotides are made starting with ribonucleotide reductase (RNR). It catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates (for example, ADP to dADP). RNR works on all of the ribonucleoside diphosphates. NDPK converts all of the nucleoside diphosphates to nucleoside triphosphates using energy from other triphosphates.
13. The pathway to making thymidine nucleotides is more complicated. It goes from UDP to dUDP (RNR), then to dUTP (NDPK) then to dUMP (dUTPase), then to dTMP (thymidylate synthase). The last reaction requires folate to put the methyl group onto the U to make it a T.
14. Spina bifida (incomplete closing of the neural tube in infants) has been linked to a deficiency of folic acid and a 70% reduction in the disease is realized when folic acid is supplemented in the mother's diet during pregnancy.
- published: 11 Feb 2014
- views: 4189
The Dangers of MSG - Part 4 'Avoiding the MSG Threat' (Flavor Enhancers E621 side effects)
- Order: Reorder
- Duration: 7:11
- Updated: 10 Mar 2008
- views: 64005
Part 4 in this series about MSG (E621) will show how to avoid it in grocery stores and restaurants as MSG has many hidden names!
MSG is used in thousands of p...
Part 4 in this series about MSG (E621) will show how to avoid it in grocery stores and restaurants as MSG has many hidden names!
MSG is used in thousands of products, such as snacks, soups, sauces, meats, flavored potato chips, fast food and Chinese food.
http://naturalnews.com/034272_MSG_monosodium_glutamate.html
http://saynotomsg.com/basics_list.php
MSG is also known as Ajinomoto, Accent, vetsin or umami. MSG is 'hidden' in many other names, such as yeast extract, hydrolised protein, natural flavoring, etc.
http://truthinlabeling.org/hiddensources_printable.pdf
http://msgmyth.com/hidden_names_for_msg.html
MSG makes food taste better but it's NOT safe!
http://naturalnews.com/034031_MSG_health_effects.html
The harmful side effects of MSG include headaches, allergies, growth disruptions, hormonal imbalance, learning disorders, ADHD, behavioral problems, autism, muscle pain, nerve pain, heart attacks and irregularities, impaired circulation, skin rashes, retina damage, stomach, intestine and respiration problems, obesity, cancer, etc.
http://msgtruth.org/body.htm
http://naturalnews.com/024438.html
Many problems don't become obvious until puberty. This is caused by poor functioning of the hormones due to exposure to MSG in the first few years of life.
Dr. John Olney discovered in 1969 that MSG caused brain damage and obesity in mice.
http://personalhealthinformationguide.blogspot.com.es/2010/03/msg-causes-rapid-brain-cell-death.html
http://msgtruth.org/obesity.htm
Enormous amounts of flavor enhancers are added to our food. Governmental agencies such as the US Food & Drug Administration insist that MSG is perfectly safe. But research that 'proves' that MSG is safe is financed by the food industry itself...
"My people are destroyed for lack of knowledge."
Hosea 4:6 (KJV)
Avoid MSG and discover how your health will improve dramatically!
http://msgtruth.org/avoid.htm
For more insight on the toxicity of MSG please watch the film 'Sweet Misery' (start watching at 34:00).
http://youtube.com/watch?v=usGh-SRUWBQ
Insightful book about MSG 'Excitotoxins: The Taste That Kills' by Dr. Russell Blaylock, MD.
http://amazon.com/Excitotoxins-The-Taste-That-Kills/dp/0929173252
http://youtube.com/watch?v=tTSvlGniHok
Additives that ALWAYS contain MSG:
gelatin, calcium caseinate, sodium caseinate, monosodium glutamate, hydrolyzed vegetable protein (HVP), textured protein (including TVP), hydrogenated vegetable oil, autolyzed plant protein, monopotassium glutamate, hydrolyzed protein, hydrolyzed plant protein (HPP), hydrolyzed oat flour, corn oil, plant protein extract, sodium caseinate, glutamate, glutamic acid, yeast extract, yeast food or nutrient, autolyzed yeast.
Additives that OFTEN contain MSG:
natural flavors, flavors, flavoring, seasonings, broth, bouillon, malted barley, modified food starch, barley malt, reaction flavors, rice syrup or brown rice syrup, stock, malt extract or flavoring, natural chicken, beef or pork flavoring, maltodextrin, dextrose, dextrates, lipolyzed butter fat, caramel flavoring (coloring), soy protein, soy sauce or extract, soy protein iIsolate or concentrate, corn syrup and corn syrup solids, high fructose corn syrup, citric acid, cornstarch fructose, milk powder, dry milk solids, protein fortified milk, carrageenan, wheat, rice, corn or oat protein, flowing agents, whey protein or whey, anything enriched or vitamin enriched, protein fortified 'anything', annatto, whey protein isolate or concentrate, yeast nutrients, enzyme modified 'anything', spice, pectin, guar and vegetable gums, ultra-pasteurized 'anything', dough conditioners, lecithin, protease, protease enzymes, fermented 'anything', gluten and gluten flour, protein powders (whey, soy, oat, and rice) used in protein bars, shakes and body building drinks, amino acids, wheat/ barley grass powders, artificial flavor.
The names and E-numbers of harmful flavor enhancers:
E620 Glutamic acid
E621 Monosodium glutamate
E622 Monopotassium glutamate
E623 Calcium diglutamate
E624 Monoammonium glutamate
E625 Magnesium diglutamate
E626 Guanylic acid
E627 Disodium guanylate
E628 Dipotassium guanylate
E629 Calcium guanylate
E630 Inosinic acid
E631 Disodium inosinate
E632 Dipotassium inosinate
E633 Calcium inosinate
E634 Calcium 5'-ribonucleotides
E635 Disodium 5'-ribonucleotide
E636 Maltol
E637 Ethylmaltol
Playlist 'The Dangers of MSG (E621)'
http://youtube.com/view_play_list?p=E7C6A9A386BB500E
More information about MSG:
http://msgmyth.com
http://saynotomsg.com
http://truthinlabeling.org
http://msgtruth.org
http://kisswebpage.com/msg
http://feingold.org/Research/msg.html
http://msgtruth.org/related.htm
http://www.advancedhealthplan.com/msgstudy.html
http://science.naturalnews.com
My video playlist 'Dangers in our Food':
http://youtube.com/playlist?list=PLxeNMshhLFQI1ZObMI4zuntcg71ufNBpg
HealthRanger7
http://youtube.com/HealthRanger7
wn.com/The Dangers Of Msg Part 4 'Avoiding The Msg Threat' (Flavor Enhancers E621 Side Effects)
Part 4 in this series about MSG (E621) will show how to avoid it in grocery stores and restaurants as MSG has many hidden names!
MSG is used in thousands of products, such as snacks, soups, sauces, meats, flavored potato chips, fast food and Chinese food.
http://naturalnews.com/034272_MSG_monosodium_glutamate.html
http://saynotomsg.com/basics_list.php
MSG is also known as Ajinomoto, Accent, vetsin or umami. MSG is 'hidden' in many other names, such as yeast extract, hydrolised protein, natural flavoring, etc.
http://truthinlabeling.org/hiddensources_printable.pdf
http://msgmyth.com/hidden_names_for_msg.html
MSG makes food taste better but it's NOT safe!
http://naturalnews.com/034031_MSG_health_effects.html
The harmful side effects of MSG include headaches, allergies, growth disruptions, hormonal imbalance, learning disorders, ADHD, behavioral problems, autism, muscle pain, nerve pain, heart attacks and irregularities, impaired circulation, skin rashes, retina damage, stomach, intestine and respiration problems, obesity, cancer, etc.
http://msgtruth.org/body.htm
http://naturalnews.com/024438.html
Many problems don't become obvious until puberty. This is caused by poor functioning of the hormones due to exposure to MSG in the first few years of life.
Dr. John Olney discovered in 1969 that MSG caused brain damage and obesity in mice.
http://personalhealthinformationguide.blogspot.com.es/2010/03/msg-causes-rapid-brain-cell-death.html
http://msgtruth.org/obesity.htm
Enormous amounts of flavor enhancers are added to our food. Governmental agencies such as the US Food & Drug Administration insist that MSG is perfectly safe. But research that 'proves' that MSG is safe is financed by the food industry itself...
"My people are destroyed for lack of knowledge."
Hosea 4:6 (KJV)
Avoid MSG and discover how your health will improve dramatically!
http://msgtruth.org/avoid.htm
For more insight on the toxicity of MSG please watch the film 'Sweet Misery' (start watching at 34:00).
http://youtube.com/watch?v=usGh-SRUWBQ
Insightful book about MSG 'Excitotoxins: The Taste That Kills' by Dr. Russell Blaylock, MD.
http://amazon.com/Excitotoxins-The-Taste-That-Kills/dp/0929173252
http://youtube.com/watch?v=tTSvlGniHok
Additives that ALWAYS contain MSG:
gelatin, calcium caseinate, sodium caseinate, monosodium glutamate, hydrolyzed vegetable protein (HVP), textured protein (including TVP), hydrogenated vegetable oil, autolyzed plant protein, monopotassium glutamate, hydrolyzed protein, hydrolyzed plant protein (HPP), hydrolyzed oat flour, corn oil, plant protein extract, sodium caseinate, glutamate, glutamic acid, yeast extract, yeast food or nutrient, autolyzed yeast.
Additives that OFTEN contain MSG:
natural flavors, flavors, flavoring, seasonings, broth, bouillon, malted barley, modified food starch, barley malt, reaction flavors, rice syrup or brown rice syrup, stock, malt extract or flavoring, natural chicken, beef or pork flavoring, maltodextrin, dextrose, dextrates, lipolyzed butter fat, caramel flavoring (coloring), soy protein, soy sauce or extract, soy protein iIsolate or concentrate, corn syrup and corn syrup solids, high fructose corn syrup, citric acid, cornstarch fructose, milk powder, dry milk solids, protein fortified milk, carrageenan, wheat, rice, corn or oat protein, flowing agents, whey protein or whey, anything enriched or vitamin enriched, protein fortified 'anything', annatto, whey protein isolate or concentrate, yeast nutrients, enzyme modified 'anything', spice, pectin, guar and vegetable gums, ultra-pasteurized 'anything', dough conditioners, lecithin, protease, protease enzymes, fermented 'anything', gluten and gluten flour, protein powders (whey, soy, oat, and rice) used in protein bars, shakes and body building drinks, amino acids, wheat/ barley grass powders, artificial flavor.
The names and E-numbers of harmful flavor enhancers:
E620 Glutamic acid
E621 Monosodium glutamate
E622 Monopotassium glutamate
E623 Calcium diglutamate
E624 Monoammonium glutamate
E625 Magnesium diglutamate
E626 Guanylic acid
E627 Disodium guanylate
E628 Dipotassium guanylate
E629 Calcium guanylate
E630 Inosinic acid
E631 Disodium inosinate
E632 Dipotassium inosinate
E633 Calcium inosinate
E634 Calcium 5'-ribonucleotides
E635 Disodium 5'-ribonucleotide
E636 Maltol
E637 Ethylmaltol
Playlist 'The Dangers of MSG (E621)'
http://youtube.com/view_play_list?p=E7C6A9A386BB500E
More information about MSG:
http://msgmyth.com
http://saynotomsg.com
http://truthinlabeling.org
http://msgtruth.org
http://kisswebpage.com/msg
http://feingold.org/Research/msg.html
http://msgtruth.org/related.htm
http://www.advancedhealthplan.com/msgstudy.html
http://science.naturalnews.com
My video playlist 'Dangers in our Food':
http://youtube.com/playlist?list=PLxeNMshhLFQI1ZObMI4zuntcg71ufNBpg
HealthRanger7
http://youtube.com/HealthRanger7
- published: 10 Mar 2008
- views: 64005
back
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- Chat
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- Playlist
- Chat
0:35
Inosinic acid Meaning
Video shows what inosinic acid means. a nucleotide, inosine phosphate, found in muscle tis...
published: 26 Apr 2015
Inosinic acid Meaning
Inosinic acid Meaning
- Report rights infringement
- published: 26 Apr 2015
- views: 30
13:04
Synthesis of Purine Nucleotides (Easy)
Biosynthesis of purines (adenosine and guanine) from ribose-5-phosphate (this occurs in th...
published: 30 Apr 2016
Synthesis of Purine Nucleotides (Easy)
Synthesis of Purine Nucleotides (Easy)
- Report rights infringement
- published: 30 Apr 2016
- views: 570
28:00
Rika's TOKYO CUISINE Chicken Breast and Umeboshi Rice - Dining with the Chef
In this episode, we'll be making rice with healthy chicken breast and umeboshi pickled plu...
published: 11 Oct 2016
Rika's TOKYO CUISINE Chicken Breast and Umeboshi Rice - Dining with the Chef
Rika's TOKYO CUISINE Chicken Breast and Umeboshi Rice - Dining with the Chef
- Report rights infringement
- published: 11 Oct 2016
- views: 16
2:02
Disodium inosinate
Disodium inosinate is the disodium salt of inosinic acid with the chemical formula C10H11N...
published: 22 Dec 2015
Disodium inosinate
Disodium inosinate
- Report rights infringement
- published: 22 Dec 2015
- views: 104
49:34
#39 Biochemistry Nucleotide Metabolism I Lecture for Kevin Ahern's BB 451/551
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Downl...
published: 10 Feb 2012
#39 Biochemistry Nucleotide Metabolism I Lecture for Kevin Ahern's BB 451/551
#39 Biochemistry Nucleotide Metabolism I Lecture for Kevin Ahern's BB 451/551
- Report rights infringement
- published: 10 Feb 2012
- views: 10480
0:27
Inosinate Meaning
Video shows what inosinate means. any salt or ester of inosinic acid, the salts are used a...
published: 26 Apr 2015
Inosinate Meaning
Inosinate Meaning
- Report rights infringement
- published: 26 Apr 2015
- views: 42
1:01
極旨！キンキの開き。 Super Yum! Cut-open and dried Channel Rockfish
巨大サイズのキンキの開き。根室の潮風が最高のスパイス！
Huge size of cut-open and dried Channel Rockfish.
This is tra...
published: 13 May 2016
極旨！キンキの開き。 Super Yum! Cut-open and dried Channel Rockfish
極旨！キンキの開き。 Super Yum! Cut-open and dried Channel Rockfish
- Report rights infringement
- published: 13 May 2016
- views: 40
47:37
Kevin Ahern's Bite-Sized Biochemistry #39 - Nucleotide Metabolism I
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Downl...
published: 03 Aug 2011
Kevin Ahern's Bite-Sized Biochemistry #39 - Nucleotide Metabolism I
Kevin Ahern's Bite-Sized Biochemistry #39 - Nucleotide Metabolism I
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- published: 03 Aug 2011
- views: 6399
49:21
39. Kevin Ahern's Biochemistry - Nucleotide Metabolism II
1. Contact me at kgahern@davincipress.com / Friend me on Facebook (kevin.g.ahern)
2. Downl...
published: 11 Feb 2014
39. Kevin Ahern's Biochemistry - Nucleotide Metabolism II
39. Kevin Ahern's Biochemistry - Nucleotide Metabolism II
- Report rights infringement
- published: 11 Feb 2014
- views: 4189
7:11
The Dangers of MSG - Part 4 'Avoiding the MSG Threat' (Flavor Enhancers E621 side effects)
Part 4 in this series about MSG (E621) will show how to avoid it in grocery stores and res...
published: 10 Mar 2008
The Dangers of MSG - Part 4 'Avoiding the MSG Threat' (Flavor Enhancers E621 side effects)
The Dangers of MSG - Part 4 'Avoiding the MSG Threat' (Flavor Enhancers E621 side effects)
- Report rights infringement
- published: 10 Mar 2008
- views: 64005
Inosinic acid Meaning...
Synthesis of Purine Nucleotides (Easy)...
Rika's TOKYO CUISINE Chicken Breast and Umeboshi R...
Disodium inosinate...
#39 Biochemistry Nucleotide Metabolism I Lecture f...
Inosinate Meaning...
極旨！キンキの開き。 Super Yum! Cut-open and dried Channel R...
Kevin Ahern's Bite-Sized Biochemistry #39 - Nucleo...
39. Kevin Ahern's Biochemistry - Nucleotide Metab...
The Dangers of MSG - Part 4 'Avoiding the MSG Thre...
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Islamic State Founder Bahgdadi Hunkers Down in Mosul, Reports Say
Edit Voa News 19 Oct 2016
Islamic State commanders, including founder Abu Bakr al-Baghdadi, are huddling in bunkers in Mosul, where they are directing the defense against an Iraqi-led offensive to retake the city, Iraqi military intelligence officials say ... Baghdadi, the Muslim fundamentalist religious teacher who declared the caliphate in Mosul in 2014, is one of the key targets for the invading Kurdish and Iraqi forces....
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UPDATE: Northeast Philippine Coast Bears Brunt Of Super Typhoon Haima
Edit WorldNews.com 20 Oct 2016
The northeastern Philippine coast bore the initial brunt of Super Typhoon Haima as it pounded the area with ferocious winds and rain reminiscent of the catastrophe wrought by 2013’s Typhoon Haiyan, The Associated Press reported. With sustained winds of 225 kilometers (140 mph) and gusts of up to 315 kph (195 mph) Haima made landfall at Penablanca town in Cagayan province shortly before midnight, weather officials said....
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Russian Hacker Suspected Of US Cyberattacks Arrested By Czech Police: Report
Edit WorldNews.com 19 Oct 2016
A Russian hacker suspected of cyberattacks in the United States has been arrested by Czech police, officials told the Associated Press Wednesday.Police said an international warrant for the man, who was not identified, was issued by Interpol and officers cooperated with the US Federal Bureau of Investigation on the case, the report said. Police spokesman Jozef Bocan said the man was arrested in a Prague hotel....
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Saudi Arabia Executes Royal Family Member for Murder
Edit Bloomberg 19 Oct 2016
A Saudi prince has been executed after he was convicted of murder, a rare punishment for a member of the royal family in the conservative kingdom. Prince Turki bin Saud bin Turki bin Saud Al Kabir was found guilty of shooting another Saudi national after a brawl ... Twitter. Mohamad Bazzi on Twitter ... ....
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Michael Moore Premieres US Presidential Election Film
Edit WorldNews.com 19 Oct 2016
Filmmaker Michael Moore has premiered a surprise film discussing the presidential election just three weeks before Americans head to vote in the next quadrennial election, The Associated Press reported Wednesday.The film premiered in New York Tuesday night in front of an audience of his fans, The Hollywood Reporter said ... It will also be shown at a theater in Encino, California.Moore says he hopes more theaters will be announced soon. ....
Man attacks estranged wife with acid after argument
Edit The Hindu 20 Oct 2016
A 19-year-old woman was allegedly attacked with acid by her estranged husband following an argument at a park in Rohini on Tuesday evening ... The second time, she said, he dragged her and rubbed her body over the acid that fell on the ground ... In an attempt to save her, she said, some acid fell on Pradeep as well ... His mother, Harjinder Kaur, claimed that her son was innocent and that it was Amanpreet who was carrying the acid in a bottle....
Cheruvathery residents on warpath against jewellery unit
Edit The Times of India 20 Oct 2016
Residents of Cheruvathery near Avinissery began an indefinite strike in front of district collectorate on Wednesday seeking action against a gold jewellery manufacturing unit here alleging that the acidic effluent from the company had polluted the wells in the neighbourhood ... The water in the well is acidic and children fell ill whenever we used it," said Valsan, a resident....
0398 - 10/19/16 (https://emergency.cdc.gov/han/han00398.asp) (CDC - Centers for Disease Control and Prevention)
Edit Public Technologies 20 Oct 2016
(Source. CDC - Centers for Disease Control and Prevention). Distributed via the CDC Health Alert Network. October 19, 2016, 1700 ET (5.00 PM ET). CDCHAN-00398. Summary. The U.S ... In addition, CDC has made specific recommendations for areas of identified active transmission ... Symptomatic pregnant women who are evaluated less than two weeks after symptom onset should receive serum and urine Zika virus RNA nucleic acid test (NAT) testing ... (noodl....
Acid-laden truck topples in Thane, school in vicinity shut
Edit Deccan Herald 19 Oct 2016
An acid-laden container truck overturned on the busy Ghodbunder road here this morning and the leaking acid's fumes spread in the area, prompting authorities to evacuate a school in the vicinity....
Man attacks wife with acid in Juna Vadaj
Edit The Times of India 19 Oct 2016
A 32-year-old woman was attacked with acid by her husband near Juna Vadaj bus stand on Tuesday afternoon ... When talks failed, he pulled out a bottle of acid out and threw it on Heena before fleeing. Sources said the husband is a balloon vendor and thus he had acid handy, which is used to make helium to inflate balloons....
Comic book features stories of acid attack survivors
Edit The Times of India 19 Oct 2016
Two years after the release of a comic book on rape victims-turned-superheroes, the creators of 'Priya's Shakti' have come out with a sequel featuring acid attack survivors in India and around the world ... The book shows Priya, the protagonist from the first book, joining forces with a group of acid attack survivors to fight the demon-king, Ahankar....
Brazil Acetic Acid Market Review 2016-2020 - Research and Markets
Edit Business Wire 19 Oct 2016
DUBLIN--(BUSINESS WIRE)--Research and Markets has announced the addition of the "Acetic Acid Market in Brazil. 2016-2020 Review" report to their offering. The report brings together facts and figures about acetic acid market in Brazil covering period of 2010-2020. Statistics, experts' opinions and estimations are given. The report about acetic acid market in Brazil covers ... ....
Neu5Gc in red meat and organs may pose a significant health hazard (UC Davis Health System)
Edit Public Technologies 19 Oct 2016
Neu5Gc, a non-human sialic acid sugar molecule common in red meat that increases the risk of tumor formation in humans, is also prevalent in pig organs, with concentrations increasing as the organs are cooked, a study by researchers from the UC Davis School of Medicine and Xiamen University School of Medicine has found ... acids are poorly understood....
Folinic acid may help autistic kids improve skills
Edit Newstrack India 19 Oct 2016
The findings are from a placebo-controlled trial in which children were randomised to receive either high-dose folinic acid or a placebo ... In the current study, these researchers found that participants with folate receptor autoantibodies had a more favourable response to the folinic acid treatment....
Cancer survivors share tales of determination and recovery
Edit The Times of India 19 Oct 2016
Coimbatore ... A severe bout of acid refluxes and chronic acidity took him to the hospital in 2001. He was operated for acidity, only for the problem to recur. "In 2002, when I went back complaining of severe acidity, the doctors did a battery of tests and informed me that I was at an advanced stage of stomach cancer, and the chances of survival were slim," he said ... RELATED. From around the web....
Harry Potter star 'stunned witless' at cafe run by acid attack survivors
Edit The Times of India 19 Oct 2016
British actor Jason Isaacs, known for his performance as Lucius Malfoy in the Harry Potter films, paid a secret visit to Sheroes Hangout, the only café in India run entirely by acid attack survivors. Isaacs, who had come here with his wife and two daughters, went unrecognized at first as he ordered food in the cafe and chatted up it's all-women acid attack survivors staff ... It is run by magnificent acid attack survivors."....
Evonik starts construction of second methionine complex in Singapore (Evonik Industries AG)
Edit Public Technologies 19 Oct 2016
Evonik Industries plans to build a second world-scale plant for the production of the amino acid DL-methionine in Singapore are fully on schedule ... The specialty chemicals company produces the amino acid in its world-scale plants in Antwerp (Belgium), Wesseling/Cologne (Germany), Mobile (Alabama, USA), and Singapore. DL-methionine is an essential amino acid, which must be absorbed through feed intake....
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