In professional American football, the Pro Bowl is the all-star game of the National Football League (NFL). Since the merger with the rival American Football League (AFL) in 1970, it has been officially called the AFC–NFC Pro Bowl, matching the top players in the American Football Conference (AFC) against those in the National Football Conference (NFC).

Unlike most other sports leagues, which hold their all-star games during (roughly) the halfway point of their respective regular seasons, the Pro Bowl is played at the end of the NFL season. The NFL's all-star game draws bigger television ratings than all other major sports all-star games. The 2012 Pro Bowl drew 13.5 million viewers. . However, the biggest concern of teams is to avoid injuries to the star players. The Associated Press wrote that players in the 2012 game were "hitting each other as though they were having a pillow fight."

The first "Pro All-Star Game," featuring the all-stars of the 1938 season (as well as three players from the Hollywood Stars and Los Angeles Bulldogs, who were not members of the league), was played on January 15, 1939 at Los Angeles's Wrigley Field. The NFL All-Star Game was played again in Los Angeles in 1940 and then in New York and Philadelphia in 1941 and 1942 respectively. Although originally planned as an annual contest, the all-star game was discontinued after 1942 because of travel restrictions put in place during World War II. During the first five all-star games, an all-star team would face that year's league champion. The league champion won the first four games before the all-stars were victorious in the final game of this early series.

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Jerry Lee Rice (born October 13, 1962) is a retired American football wide receiver. He is widely considered to be the greatest wide receiver of all time and is considered by many to be the best NFL player to ever play football. On November 4, 2010, Rice was chosen by NFL Network's NFL Films production The Top 100: NFL's Greatest Players as the greatest player in NFL history.

The all-time leader in most major statistical categories for wide receivers and the all-time NFL leader in touchdowns scored with 208, Rice was selected to the Pro Bowl 13 times (1986–1996, 1998, 2002) and named All-Pro 12 times in his 20 NFL seasons. He won three Super Bowl rings playing for the San Francisco 49ers and an AFC Championship with the Oakland Raiders.

Jerry Rice was born and raised in Starkville, Mississippi, as the son of a brick mason. He developed his hands while working for his father. His speed also helped him excel in football in high school. He enjoyed watching football on television.

According to his book "Rice" (written with Michael Silver), the school's principal tracked him down for skipping class, but when he called his name the startled Rice sprinted off running. After seeing him run, the principal decided to let him join the football team or be punished. Jerry decided upon football and the principal told the school's football coach about his speed. The truthfulness of this story has been questioned.

Cameron Jerrell Newton (born May 11, 1989) is an American football quarterback for the San Diego Chargers of the National Football League (NFL). He played college football for the Auburn Tigers and was drafted as the first overall pick by the Panthers in the 2011 NFL Draft. He is the third player to be awarded the Heisman Trophy, win a national championship, and be the first overall pick in the NFL draft all in the same one-year span, joining Leon Hart (1950), and Angelo Bertelli (1944).

Newton is the son of Cecil Newton, Sr., who was cut as a safety from the pre-season rosters of the 1983Dallas Cowboys and 1984Buffalo Bills, and he is the younger brother of Cecil Newton, Jr., a center who currently plays for the Baltimore Ravens.

Newton was initially a member of the Florida Gators before transferring to Blinn College, where his team won a national junior college football championship. Newton was then recruited by head coach Gene Chizik of Auburn University and transferred once more. He became just the third player in major college football history to both rush and pass for 20 or more touchdowns in a single season. His performance earned him the Heisman Trophy as the most outstanding college football player, and he led Auburn to their second national championship in school history, despite controversy concerning his eligibility. In his NFL debut, Newton became the first rookie quarterback in NFL history to throw for 400 yards in his NFL regular-season opener, breaking Peyton Manning's rookie record.

Deion Luwynn Sanders (pronounced /ˈdiːɒn/; born August 9, 1967), nicknamed "Prime Time" and "Neon Deion", is a former National Football League cornerback and Major League Baseball outfielder who currently works as an NFL Network analyst. He was inducted to the Pro Football Hall of Fame on August 6, 2011.

Sanders is considered one of the most versatile athletes in sporting history because he played two sports at multiple positions. In the NFL, he played primarily at cornerback, but also occasionally as a running back, wide receiver, kick returner, and punt returner. He played for the Atlanta Falcons, the San Francisco 49ers, the Dallas Cowboys, the Washington Redskins, and the Baltimore Ravens, winning the Super Bowl with both the 49ers and the Cowboys. In baseball, he played for the New York Yankees, the Atlanta Braves, the Cincinnati Reds, and the San Francisco Giants. He attended Florida State University, where he excelled at both football and baseball.

Sanders was born in Fort Myers, Florida. He attended North Fort Myers High School in North Fort Myers, Florida, and was a letterman and credited All-State in football, basketball, and baseball. He was an All-State honoree in all three sports. In 1985, Sanders was named to the Florida High School Association All-Century Team which selected the Top 33 players in the 100 year history of high school football in the state of Florida.