Latest News for: histones

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Global Cancer Immunotherapy Markets, 2021-2026: Advent of New Drug Classes Including Monoclonal Antibodies and Histone Deacetylase (HDAC) Inhibitors

PR Newswire 22 Oct 2021
DUBLIN, Oct ... Immunotherapy is a kind of biological therapy ... The monoclonal segments are having a key share in the market ... The advent of new drug classes, including monoclonal antibodies and histone deacetylase (HDAC) inhibitors, designed to target receptors associated with multiple myeloma, is expected to build the market's future ... Key Topics Covered ... .
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Linker histones tune the length and shape of chromosomes

Science Daily 04 Oct 2021
A new study finds that proteins known as linker ...
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Hairless regulates heterochromatin maintenance and muscle stem cell function as a histone demethylase antagonist [Cell Biology]

PNAS 07 Sep 2021
By comparing gene-expression profiles from quiescent and activated MuSCs, we... .
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Infographic: A Yeast Model for Studying Histone Modifications

The Scientist 01 Sep 2021
The methodology involves modifying histones and displaying them on the cell surface for analysis ... .
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Yeast "Mini Labs" Help Researchers Probe Histone Modifications

The Scientist 01 Sep 2021
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression ... .
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Histone deacetylase inhibitor gel shows promise for the treatment of patients with basal cell carcinoma

Science Daily 06 Aug 2021
Remetinostat, a topical cream and first-in-class inhibitor of histone deacetylation, showed signs of clinical efficacy in patients with basal cell carcinoma. <!-- more --> ... .
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Clinical Protocols based on Molecular Cancer genetics and DNA OncoPharmaceutics to detect aberrant cellular malformations induced by DNA methylation and histone modification in the cell nucleus of the mitotic spindle and microtubule chromosomal interface to disable cancer cell replication and proliferation

PR Newswire 05 Aug 2021
... and formative inflection point and catalyst within the tumor microenvironment." The integration of DNA demethylation and HDAC -Histone Regulation via Histone Deacetylase Methyltransferase Inhibitors remains the clinical focal point of our therapeutic framework.".
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Replication-dependent histone biosynthesis is coupled to cell-cycle commitment [Cell Biology]

PNAS 29 Jul 2021
The current model of replication-dependent (RD) histone ...
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Nuclear factor Y subunit facilitates histone acetylation for salt tolerance in soybean

Phys Dot Org 22 Jul 2021
Recently, Prof Zhang Jinsong's team from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences (CAS) discovered that a nuclear factor Y (NFY) subunit GmNFYA can modify histone acetylation and activate stress-responsive genes for salt tolerance in soybean.
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Unraveling DNA packaging: How histones and DNA interact

Phys Dot Org 01 Jun 2021
A key role in DNA's compactification is played by histones, structural-support proteins around which a part of a DNA molecule can wrap. The DNA-histone wrapping process is reversible—the two molecules can unwrap and rewrap—but little is known about the mechanisms at play.
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Spreading and epigenetic inheritance of heterochromatin require a critical density of histone H3 lysine 9 ...

PNAS 25 May 2021
Heterochromatin assembly requires methylation of histone H3 lysine 9 (H3K9me) ...
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Global Histone Methyltransferases Market Will Be Fiercely Competitive by Top Companies in 2027

The Sentinel Newspaper 23 May 2021
This global study of the Histone Methyltransferases Systems market offers an overview of the existing market trends, metrics, drivers, and restrictions and also offers a point of view for important segments ... Request a FREE PDF Sample Report copy Of Histone Methyltransferases Market Here@ ... Global Histone Methyltransferases Business Analysis.
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The Secret Role Histones Played in Complex Cell Evolution

Wired 16 May 2021
New work shows that the proteins, long treated as boring spools for DNA, are key to the origin story for eukaryotes and still play important roles in disease ... .
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