The Tōhoku region (東北地方, Tōhoku-chihō^?) is a geographical area of Japan. The region occupies the northeastern portion of Honshu, the largest island of Japan. The region consists of six prefectures (ken): Akita, Aomori, Fukushima, Iwate, Miyagi and Yamagata.

Tōhoku retains a reputation as a remote region, offering breathtaking scenery but a harsh climate. In the 20th century, tourism became a major industry in the Tōhoku region.

The area was historically known as the Michinoku region or province. a term first recorded in Hitachi-no-kuni Fudoki (常陸国風土記^?) (654). There is some variation in modern usage of the term "Michinoku".

Tōhoku's initial historical settlement occurred between the seventh and ninth centuries, well after Japanese civilization and culture had become firmly established in central and southwestern Japan. The last stronghold of the indigenous Emishi on Honshu and the site of many battles.

The haiku poet Matsuo Bashō wrote Oku no Hosomichi (The Narrow Road to the Deep North) during his travels through Tōhoku.