Flomoxef
FLOMOXEF is a broad-spectrum oxacephem (oxacephalosporin) antibiotic. Flomoxef exhibits a broad spectrum of antibacterial activity against G(+), G(-) and even anaerobes such as Staphylococcus sp., Escherichia coli, and Bacteroides sp., and it can be used singly to treat infection caused by aerobes and anaerobes (Mixed infection) effectively. Flomoxef belongs to the cephamycin, so it is very stable against β-lactamase as well as Extended Spectrum β-lactamase (ESBL), a novel resistance induced by Enterobacteriaceae. There is no Oxyimino group in the structure of Flomoxef, so it won’t derive ESBL and it is also effective for the treatment to ESBL infection. No disulfiram-like reaction and less incidence of vitamin K deficiency than that of Latamoxef.
Indications: The following infections caused by Flomoxef sodium susceptible strains: Staphylococcus spp., Streptococcus spp.(excluding Enterobacter), Streptococcus pneumoniae, Branhamella catarrhalis, Neisseria gonorrhoeae, E. coli, Klebsiella spp., Proteus spp., Influenzae spp., Peptostreptococcus spp.、Bacteroides spp.。ex. Septicemia, Cholecystitis,, Cholangitis, Peritonitis, Bronchitis, Bronchiectasis, AECB, Pyelonephritis, Cystitis, Prostatitis, Pyelonephritis, Pneumonia.