O-2172 is a drug developed by Organix Inc, which acts as a stimulant and potent dopamine reuptake inhibitor. It is an analogue of methylphenidate where the phenyl ring has had a 3,4-dichloro substitution added, and the piperidine ring has been replaced by cyclopentane. It is around 1/3 the potency of methylphenidate, demonstrating that even with the important binding group of the nitrogen lone pair removed entirely, selective DAT binding and reuptake inhibition is still possible.

The Simplicity Pattern Company is a manufacturer of sewing pattern guides, under the "Simplicity Pattern," "It's So Easy" and "New Look" brands. The company, now owned by Wrights, began in 1927 in New York City. During the Great Depression, Simplicity allowed home seamstresses to create fashionable clothing in a reliable manner. The patterns have been manufactured in Niles, Michigan since 1931, but the products are distributed and sold in Canada, England, and Australia. In some markets, the patterns are sold by Burda, and they are sold by third party distributors in Mexico and South Africa. The company licenses its name to the manufacture of non-textile materials such as sewing machines, doll house kits, and sewing supplies.

Each Simplicity pattern has step-by-step instructions for the cutting, stitching, and assembling of clothes. Simplicity aims to emulate fashion designer clothing, and the company currently produces over 1,600 patterns.

Simplicity Patterns, like most home sewing patterns, consist of tissue paper with numbers and instructions written on it. This paper is pinned on the fabric to be sewn. The hobbyist then stitches and cuts along the printed lines to create the finished clothing.