Jun dimerization protein 2 (JUNDM2) is a protein that in humans is encoded by the JDP2 gene. The Jun dimerization protein is a member of the AP-1 family of transcription factors.
JDP 2 was found by a Sos-recruitment system, to dimerize with c-Jun to repress AP-1-mediated activation. It was later identified by the yeast-two hybrid system to bind to activating transcription factor 2 (ATF2) to repress ATF-mediated transcriptional activation. JDP2 regulates 12-O-tetradecanoylphorbol-13-acetate (TPA) response element (TRE)- and cAMP-responsive element (CRE)-dependent transcription.
The JDP2 gene is located on human chromosome 14q24.3 (46.4 kb, 75,427,715 bp to 75,474,111 bp) and mouse chromosome 12 (39 kb, 85,599,105 bp to 85,639,878 bp), which is located at about 250 kbp in the Fos-JDP2-BATF locus.Alternative splicing of JDP2 generates at least two isoforms. The protein JDP2 has 163 amino acids, belongs to the family of basic leucine zipper (bZIP), and shows high homology with the ATF3 bZIP domain. The bZIP domain includes the amino acids from position 72 to 135, the basic motif from position 74 to 96, and the leucine zipper from 100 to 128. The molecular weight of the canonical JDP2 is 18,704 Da. The histone-binding region is located from position 35 to 72 and the inhibition of the histone acetyltransferase (INHAT) region is from position 35 to 135, which is located before the DNA-binding domain.
JDP may refer for:
In business:
In architecture:
In politics:
Other:
Gotta giddy up...
Gotta giddy up...
'N Sync - giddy up... like this
Gotta giddy up..
C'mon...just drop the verse
Gotta giddy up...
Tried to get a hold of you last night
Called you on the phone
Thinkin' to myself something ain't right
Girl were you alone?
Letting little things come between us
All we do is fuss
When all I wanna do is show you love
So I say, Hold up!
I'm tired of all these lies...yeah, yeah
Hold up!
And if you wanna make things right
That's right
Hold up!
I'm tired of all these lies
Hold up!
Cause if you wanna make things right, you got to..
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
I Gotta giddy up
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
Gotta giddy up
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I gotta giddy up, giddy up
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
Gotta giddy up
Remembering the way we used to be
Everything was cool
And now you've gone and done all this to me babe (to me])
Maybe we can turn this love around
Give it one more try
You see everytime you're thinkin about saying goodbye
I gotta I say, Hold up!
I'm tired of all these lies
Hold up!
If you wanna make things right
Hold up!
I'm tired of all these lies
Hold up!
Cause if you wanna make things right, you got to
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
I Gotta giddy up
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
Gotta giddy up (like this)
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
Yeah
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
Gotta giddy up
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
You better giddy up
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You gotta giddy up yeah.. up yeah...up...
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
Yeah
Giddy up, Giddy up, Giddy up now (giddy up, giddy up)
Gotta giddy up
Yeah..right... giddy up..ha..giddy up..
Ride it, Ride it, Ride it, Ride it,
Ride it, Ride it, Ride it,
Giddy up, Giddy Up
Ride it, Ride it, Ride it, Ride it,
Ride it, Ride it, Ride it,
Giddy up, Giddy Up
Ride it, Ride it, Ride it, Ride it,
Ride it, Ride it, Ride it,
Giddy up...
You got to, you got to, you got to giddy, giddy up.
You got to, you got to, you got to giddy, giddy up.
Ride it, Ride it, Ride it, Ride it...
Ride it, Ride it, Ride it...
Giddy up...
Ride it, Ride it, Ride it...
(We gonna get dis crunk!)
The Independent | 25 Jan 2021
WorldNews.com | 25 Jan 2021
ITV | 25 Jan 2021
Middle East Monitor | 25 Jan 2021