The Sanjak of Smederevo (Serbian: Смедеревски санџак, Smederevski sandžak; Turkish: Semendire Sancağı), also known as the Pashaluk of Belgrade (Turkish: Belgrad Paşalığı), was an Ottoman administrative unit (sanjak), that existed between the 15th and the outset of the 19th centuries. It was located in the territory of present day Central Serbia, Serbia. It belonged to Rumelia Eyalet between 1459 and 1541, and again between 1716 and 1717 and again 1739 and 1817 (nominally to 1830), to Budin Eyalet between 1541 and 1686, and to Temeşvar Eyalet between 1686 and 1688 and again between 1690 and 1716.

The Sanjak of Smederevo was formed after the fall of the Serbian Despotate in 1459, and its administrative seat was Smederevo. After the Ottoman Empire conquered Belgrade in 1521, the administrative seat of the Sanjak was moved to this city. Some historians believed that epic figure of Alija Đerđelez was inspired by Ali Beg Mihaloglu, the first sanjakbey of the Sanjak of Smederevo. In period when Battle of Mohács took place the sanjakbey of Smederevo was Kučuk Bali-beg.

Smederevo (Serbian Cyrillic: Смедерево, pronounced [smêderevo]) is a city and municipality in Serbia, on the right bank of the Danube, about 40 km downstream of the capital Belgrade. According to official results of the 2011 census, the city has a population of 107,528. It is the administrative center of the Podunavlje District.

Its history starts in the 1st century BC, with the conquerings of the Roman Empire, when there existed a town called Vinceia. The modern city traces its roots back to the late Middle Ages when it was the capital (1430–1439 and 1444–1459) of the last independent Serbian state before the Ottoman conquest.

In Serbian, the city is known as Smederevo (Смедерево), in Latin, Romanian and Greek as Semendria, in Hungarian as Szendrő or Vég-Szendrő, in Turkish as Semendire.

In the 7th millennium BC, the Starčevo culture existed for a millennia, succeeded by the 6th millennium BC Vinča culture that prospered in the region.

The Paleo-Balkan tribes of Dacians and Thracians emerged in the area in the 2nd millennia BC, with the Celtic Scordisci raiding the Balkans in the 3rd century BC.