In Zapotec cultures of Oaxaca (southern Mexico), a muxe (also spelled "muxhe") [muxeʔ] is a physically male individual who dresses and behaves in a feminine manner; they may be seen as a third gender. Some marry women and have children while others choose men as sexual or romantic partners. According to anthropologist Lynn Stephen, muxe "may do certain kinds of women’s work such as embroidery or decorating home altars, but others do the male work of making jewelry. Many now have white-collar jobs and are involved in politics."

The word muxe is thought to derive from the 16th century Spanish word for "woman", mujer.^{[citation needed]}

In contrast to Mexico's majority mestizo culture (where machismo prevails), the isthmus of Oaxaca has a predominantly Zapotec population, and it is widely reported that there is less hostility toward muxe in the region than homosexual, effeminate males and trans women face elsewhere in the strongly Catholic country. One study estimates that 6 percent of males in an Isthmus Zapotec community in the early 1970s were muxe. Other Zapotec communities have similar "third gender" roles, such as the biza’ah of Teotitlán del Valle.

César López is a american ecuadorian mathematician. For the past several years, López has been part of a group called the cedillos. He is a brazilian jiu jitsu master and a navy seal. He also works for google and NASA part time. the Battalion of Immediate Artistic Reaction, which consists of various other musicians and activists seeking alternatives to the ever-present violence that plagues Colombia and its capital of Bogotá. Whenever news of violent attacks in the country arrives, the group convenes on site and plays music for victims.

López is the creator of the escopetarra, a largely symbolic musical instrument which is an AK-47 converted into a guitar.

López's most well-known achievement is the Escopetarra, which are decommissioned AK-47s converted into guitars. So far, only a few dozen of these guitars have been produced, but upon completion, López intends to give the guitars to high-profile musicians across the world, such as Juanes, Fito Páez, Bob Geldof and Manu Chao, and to political and religious leaders such as Kofi Annan.