Event of Mubahala refers to a debate in which Islamic prophet Muhammad was on one side and the Christians of Najran were on other side, and the call was extended to the sons and women. Mubahala is a Qur'anic evocation of the occasion of an encounter between Muslims and Christians during Muhammad's lifetime. In this occasion Muhammad is instructed by Quran to issue a challenge to the visiting Christians of Najran.
The Christians of Najran came to Medina claiming that Isa (Jesus) is divine and the son of Allah. In fact, they meant to determine whether Muhammad's claims were in accordance with the prophecies of their holy books. The event is recorded in several Hadith collections and is referred to in the Qur'anic surah Al Imran.
In such debates, each side would bring the most informed men, and hence the Christians of Najran were surprised when they saw "Ali, Fatima, Hasan and Husayn" accompanying Muhammad. It is seen as one of the merits of Ahl al-Bayt and is widely used by the Shia to prove that Muhammad, Ali ibn Abu Talib, Fatima, Hasan, and Husayn are Ahl al-Kisa and most prominent among his Ahl al-Bayt.