- published: 05 Feb 2013
- views: 101
Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist (parasympathomimetic). It was the first centrally acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease, and was marketed under the trade name Cognex. Tacrine was first synthesised by Adrien Albert at the University of Sydney. It also acts as a histamine N-methyltransferase inhibitor.
Tacrine was the prototypical cholinesterase inhibitor for the treatment of Alzheimer's disease. William K. Summers received a patent for this use (US Patent No. 4,816,456). Studies found that it may have a small beneficial effect on cognition and other clinical measures, though study data was limited and the clinical relevance of these findings was unclear.
Tacrine has been discontinued in the US in 2013, due to concerns over safety.
I will blow yo' mind/
Haha,Yeah!
DaGrin..SoSsick on the beatz
A thousand beats in a week baby!
You know what it do,You know wat it is, But we knew what it was baby!/
DaGrin..Jooooooooooo!
Joooooooo!
V1:::
Omo 9ja ni mi/
Naija lo bi mi si/
Naija mo ti bere si ni ka ABC/
Omo naija, mo le feyin si Pepsi/
Awa naija, won n gbo wa lori BBC/
T'omode ba buru, o le fe di bad boy/
Te ba tun r'abon,o o ni kin n fun yin da si bad toy/
Momsie ni kin ma lo church bi Broda David/
Ki n ma mu lyrics j'ade ninu orin Dafiidi/
Eyin t'e rap nnkan kan te p'era yin ni rappers/
Mi inse mugu, omo mi i de de pampers/
Mi i diti, gbagbe wipe mo luti/
Mo n gbo yin, e ma koja lori BRT/
Te'n ba wo s'ole bus-stop e lo ma ti b'ole/
Mi o le fight fun e, mi n kin se Oshiomole/
O le beree mole, or ko ko mole/
Lole, mo sha mope o o le wole/
Chorus::
Molenu bi PonPon Pon Pon(x8)
Awon Ijebbu, won n fi mi sere bi Ifoko/
Mi o n se agbe to lo soko ti o moko/
Iroko, awon sissy fe mu mi s'oko/
Sokoyokoto, e ti mope olobe l'oloko/
Omo naija mi o maga, mi i mugu/
Awon Ibo, won n fi mi sere bi Ugwu/
Tan ba r'imi waa ni Ol' Boi, se u be Ibo, Se you be Anambra abi You be Imo?
But mo fi n ye won pe, I be Omo Ogun/
Ta won girls ba ri mi, won a ni omo'odun/
Bi mo se n rap, e ro wipe mo n lo'gun/
Im a soldier boy, you call me Akogun/
Last album mi to jade, wo nipe ko ta/
Tan ba gbo nisinyi, won ma fi hip-hop jo bata/
Ile oba to jona, ewa lo bu si/
****** te ro'pe e gba lowo mi, ito mo to si/
Chorus::
Molenu bi PonPon Pon Pon(x8)
Awon Artiste ni Naija, imi n nu won si ma ja/
To ma sare gbagbe bata bi ki bata e ja/
Oloun si n ba elomi se ninu yin, o si n ni hit/
To ba to time kan, e yin bawo, e e ni le fit/
E ma le, igba yen la ma mo ojuomobale/
A ma fi rap rap yin po ese yin o ni bale/
E wo mi kin n fi fale/E wo mi ki n fi hale/
T'oba wa da bi iro, oya now e je a jale/
Mo ti so fun yin tele, mi o lo si bi kan kan/
Mo ti lo s'odo lo fori mi pelu kankan/
Mo mu kankan yen, mo so si odo ko b'odo lo/
E e ni wa mi ti, anirogun, nibo lo lo?/
Everywhere ti n ba'n lo, mi o n se'ran odun kan/
Anywhere ti n ba n lo, mo fe ma lo pelu'bon/
Mo de need lati get e laarin osu kan/
O ti di dandan because say ota po gan-an/
Chorus::