South Road (route A13, B23) is a major north–south conduit in Adelaide, South Australia. Also known as Main South Road, it is Adelaide's most important arterial road.

South Road carries much of the road traffic from the southern suburbs towards the Adelaide city centre. This traffic completes its journey to the city centre via Anzac Highway.

From Anzac Hwy, South Road continues north as a western bypass of the city across many arterials, the major ones being Port Road, Regency Road and Grand Junction Road, to the junctions with the Port River Expressway and the Salisbury Highway. Until the Port River Expressway opened in 2005, the sections of South Road and Salisbury Highway between Grand Junction Road and Port Wakefield Road were known as the South Road Extension, built in the early 1990s.

To the south of Anzac Hwy, the name changes to Main South Road at the intersection of Ayliffes and Shepherds Hill Roads at Clovelly Park, and continues through Seaford (where the Victor Harbor road branches off) and runs parallel to the west coast of Fleurieu Peninsula all the way to Cape Jervis at its southern tip. The town of Old Noarlunga, South Australia was bypassed in 1972, and Old Reynella in 1964. The fully reversible Southern Expressway (M2) runs roughly parallel to South Road for 18 km from Darlington to Noarlunga and carries through traffic to reduce peak congestion. Main South Road and the Southern Expressway have 3 different intersections along the length of the roads.

Mike South, (born December 26, 1957), is a American pornographic actor, director, blogger and pornography gossip columnist.

Two of the films he directed have won AVN Awards for Best Amateur Release - Southern Belles 4 in 1997 and Southern Belles 8 in 1998.

In May 2007 South underwent surgery to remove a nerve-sheath tumor.