Bargylia was an ancient city on the coast of Caria in southwestern Anatolia (modern-day Turkey) between Iasos and Myndus. Bargylia's location corresponds to the modern Turkish town of Boğaziçi in Muğla Province.

The city was said to have been founded by Bellerophon in honour of his companion Bargylos, who had been killed by a kick from the winged horse Pegasus. Near Bargylia was the Temple of Artemis Cindyas. Strabo reports the local belief that rain would fall around the temple but never touch it. Artemis Cindyas and Pegasus appear on coinage of Bargylia.

In 201/200 BC during the Cretan War King Philip V of Macedon wintered his fleet in Bargylia when he was blockaded by the Pergamene and Rhodian fleets.

Protarchus the Epicurean philosopher, the mentor of Demetrius Lacon, was a native of Bargylia.