Santa Lucía Cotzumalhuapa (or Cotzumalguapa) is the name of a pre-Columbian Maya archaeological zone dating mainly to the Late Classic period in Mesoamerican chronology, although it was occupied since the Middle Preclassic period and there is evidence of a major development during the Late Preclassic period. The famous Stela 1 from El Baúl has one of the earliest inscriptions in Mesoamerica, with the earliest legible hieroglyphic Long Count date in Guatemala: AD 37.

Cotzumalhuapa is located on the Pacific piedmont of southern Guatemala, in the department of Escuintla, on the outskirts of the modern city. During the Late Classic period, Cotzumalhuapa was a major city that extended more than ten square kilometers, encompassing three major compounds, known as El Baul, Bilbao, and El Castillo, with extensive settlements between and around them. A corpus of more than 200 monumental sculptures are known from the city and from neighboring sites that include Palo Verde, Aguna, Palo Gordo, and others. Examples of the Cotzumalhuapa sculptural style are found across the Pacific Coast and highlands of Guatemala, and into El Salvador, where Cara Sucia marks the southeastern limit of the Cotzumalhuapa zone.