Lesbophobia (sometimes Lesbiphobia) comprises various forms of negativity toward lesbian women as individuals, as a couple or as a social group. Based on the categories of sex or biological gender, sexual orientation, lesbian identity, and gender expression, this negativity encompasses prejudice, discrimination, and abuse in addition to attitudes and feelings ranging from disdain to hostility. As such, lesbophobia is sexism against women that intersects with homophobia and vice-versa. Cynthia Petersen, a professor of law at University of Ottawa, has defined lesbophobia as also including "the fear that women have of loving other women, as well as the fear that men (including gay men) have of women not loving them."

While some people use only the more general term homophobia to describe this sort of prejudice or behavior, others believe that the terms homosexual and homophobia do not adequately reflect the specific concerns of lesbians. In particular, some lesbians argue that they experience the double discrimination of both classic homophobia and sexism. Similarly, bisexual women may prefer to use the term biphobia to refer to prejudice or abuse that they encounter which is based on their bisexual identity or behaviour, as people who identify as transgender often prefer to use the word transphobia.^{[citation needed]}