Lot-et-Garonne (French: [lɔt‿e ɡaʁɔn], Occitan: Òlt e Garona) is a department in the southwest of France named after the Lot and Garonne rivers.

Lot-et-Garonne is one of the original 83 departments created during the French Revolution on March 4, 1790. It was created from part of the provinces of Guyenne and Gascogne.

Several of the original southeastern cantons in the arrondissements of Agen and Villeneuve-sur-Lot were separated from it in 1808 to become a part of the newly ceated department of Tarn-et-Garonne.

Lot-et-Garonne is part of the current region of Aquitaine and is surrounded by the departments of Lot, Tarn-et-Garonne, Gers, Landes, Gironde, and Dordogne.

Food-processing, chemicals, and pharmaceuticals are all major industries of the department.

The inhabitants of the department are called Lot-et-Garonnais.

François Asselineau (French pronunciation: [fʁɑ̃swa asəlino]; born September 14, 1957) is a French politician and an Inspector General.  He belonged to the Rally for France (RPF), before creating his own political party, Popular Republican Union, (UPR), a movement proposing France's unilateral withdrawal from the European Union, the Eurozone and NATO. He was an announced candidate for the 2012 French presidential election but failed to muster the 500 signatures from elected politicians to run for president.

Asselineau enrolled in HEC Paris where he graduated with the MSc in Management from the Grande école program in 1980. He enrolled at École nationale d'administration (ENA) where he graduated in 1985 with the second highest honors of those specialized in economics.

After graduating from HEC Paris and before enrolling École nationale d'administration (ENA), Asselineau started his career in Japan in the department of economic expansion for National Service Overseas (CSNE). Asselineau served in 1985 as inspector General in the inspection générale des Finances.