Jacobabad or Yaqubabad (Sindhi: جیکب آباد) is the capital city of Jacobabad District, Sindh, Pakistan.This is one of old city of Sind state. The city is also the administrative centre of Jacobabad Taluka, an administrative subdivision of the district, the city is subdivided into 8 Union Councils. The city is crossed by the Pakistan Railway and many main roads of the province.

During British rule, as part of British Raj, the town was the administrative headquarters of the Upper Sind Frontier District of the Bombay Presidency; with a station on the Quetta branch of the North-Western Railway. It became well known for consistently having the highest temperature in the South Asia, and has a mean summer average of 98°F, and during the month of June the temperature can consistently reach between 120° and 131°F (49 to 55°C).

The town was founded on the site of the village of Khangarh in 1847 by General John Jacob, for many years commandant of the Sind Horse, who died here in 1858. A memorial exists at the Victoria Tower in the heart of the city.