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Monday, 30 December 2013

Lrp5

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ABCG5
ABCG8
APOA2
APOA4
APOA5
Apolipoprotein
Apolipoprotein A1
Apolipoprotein B
Apolipoprotein C1
Apolipoprotein C2
Apolipoprotein C3
Apolipoprotein C4
Apolipoprotein D
Apolipoprotein E
Apolipoprotein H
ATC code A16
AXIN1
Calcium in biology
Catabolism
Catenin
Chondrocyte
Chylomicron
Duodenum
Endocytosis
Ensembl
Entrez
Enzyme
Frizzled
FZD4
Gene
Gene Ontology
GeneCards
Glucose tolerance
GSK3B
Hepatic lipase
HomoloGene
KLF15
LDL receptor
Lipid
Lipoprotein
Lipoprotein lipase
Lipoprotein(a)
LRP1
LRP10
LRP11
LRP12
LRP1B
LRP2
LRP3
LRP5
LRP5L
LRP6
Osteoarthritis
Phosphorylation
Promoter (biology)
Protein
Public domain
PubMed
PubMed Central
PubMed Identifier
RUNX2
SCARB1
Serotonin
Serum amyloid A
Serum amyloid A1
Template Eicosanoids
Template Glycolysis
Template Metabolism
Template PBB 4041
Template Urea cycle
TPH1
TSPAN12
UniProt
Vitamin D
WNT3A

photo: WN / Bhaskar Mallick

India Cine Audience Society activist hold the candel light to protest against the rape case in Barasat in Kolkata on Monday 17 June 2013

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Indian woman gang-raped 'twice in one night'

Al Jazeera

28 Dec 2013

Police have arrested 10 people in India after a 21-year-old woman was gang-raped twice in one night be two apparently unrelated groups of men. Six of the men arrested have been charged with gang-raping the woman on the evening of December 24, on officer said on Friday. None of the men have appeared in court ... 292 Source .. Agencies. ....(size: 1.8Kb)

photo: WN / Aaron Gilbert

Justin Bieber performs during the 'Believe Tour' at the Amway Center Orlando, Florida - January 25, 2013

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Justin Bieber's 'Believe' Tanks At Box Office?

Vibe Magazine

29 Dec 2013

Justin Bieber‘s second concert doc, Believe, chronicles a new era for the pop star, where media criticism threatens to drown out fan support ... (The Hobbit ... ....(size: 0.8Kb)

photo: US Army / Sinthia Rosario

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From MRAP to scrap: U.S. military chops up $1-million vehicles

Stars and Stripes

27 Dec 2013

BAGRAM, Afghanistan — Faced with an epidemic of deadly roadside bombs in Iraq and Afghanistan, U.S. military officials ordered up a fleet of V-hulled 16-ton armored behemoths in 2007 to help protect American soldiers and Marines ... The lumbering vehicles are so beloved that soldiers have scrawled notes of thanks on their armor. So why would the U.S ... It costs about $12,000 to crunch and dispose of a single MRAP here, said Mark E ... Lt. Gen ... Gen....(size: 7.4Kb)

photo: AP

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China formally eases one-child policy, abolishes labor camps

Reuters

28 Dec 2013

SHANGHAI (Reuters) - China formally approved on Saturday easing its decades-long one-child policy and the abolition of a controversial labor camp system, the official Xinhua news agency reported ... Previously, a couple could generally only have a second child if both parents were only children....(size: 1.4Kb)

photo: AP / Andre Penner

Protesters hold up posters depicting National Security Agency leaker Edward Snowden as they crash a Christmas ceremony where Brazil's President Dilma Rousseff delivers a speech to recycling workers and homeless people, in Sao Paulo, Brazil, Thursday, Dec. 19, 2013.

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Does 'No Such Agency' Mean No Such Democracy?

WorldNews.com

27 Dec 2013

Article by WN.com Correspondent Dallas Darling. Unlike the Central Intelligence Agency, which was brought into being by an act of congressional representatives, the National Security Agency (NSA) was founded by a secret presidential signature. For this reason it was jokingly referred to as the "No Such Agency," and it is for this reason that it is extremely anti democratic, a nemesis to and destroyer of popular rule and culture ... 197....(size: 4.9Kb)

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Over $1.8m to Medical Researchers

Scoop

19 Dec 2012

Wednesday, 19 December 2012, 4.51 pm. Press Release. Auckland Medical Research Foundation. Media Release. 19 December 2012. Auckland Medical Research Foundation Awards over $1.8m to Medical Researchers ... The Research project summaries overleaf ... ENDS ... We will test how glucose regulates Wnt signalling factors, such as LRP5/6 and β-catenin, and determine whether such regulation promotes lipid accumulation in cells of the arterial wall ... ....(size: 24.3Kb)

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Breast stem-cell research: Receptor teamwork is required and a new pathway may be involved

PhysOrg

30 May 2012

The UW researchers zeroed in on two related Wnt receptors on the cell surface--LRP5 and LRP6 ... On the other hand, LRP5 is clearly necessary for mammary stem cells to work ... In earlier research, Alexander and her team found that LRP5 and LRP6 serve different functions in the mouse mammary gland ... "Our hypothesis was that different Wnt ligands activate the Wnt pathway by preferentially signaling through either LRP5 or LRP6," Alexander says....(size: 4.5Kb)

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Low-density lipoprotein receptor-related protein 5 is a protein that in humans is encoded by the LRP5 gene.

LRP5 is a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with diabetes mellitus type 1 in humans. This protein plays a key role in skeletal homeostasis.

The LRP5 promoter contains binding sites for KLF15 and SP1. In addition, 5' region region of the LRP5 gene contains four RUNX2 binding sites. Conversely, LRP5 has been claimed to inhibit expression of TPH1, the rate-limiting biosynthetic enzyme for serotonin in enterochromaffin cells of the duodenum and that excess plasma serotonin leads to inhibition in bone. This view is contested by other research indicating a direct effect of LRP5 on bone.

LRP5 has been shown to interact with AXIN1.