Grahamstown (Afrikaans: Gramstad) is a city in the Eastern Cape Province of the Republic of South Africa and is the seat of the Makana municipality. The population of greater Grahamstown, as of 2003, was 124,758. The population of the surrounding areas, including the actual city was 41,799 of which 77.4% were black, 11.8% Coloured, 10% white, and 0.7% Asian. Since 1994, there has been a considerable influx of Black people from the former Ciskei Xhosa homeland, which lies just to the east. The city proper has an overwhelming white majority, while the neighboring townships (geographically separate, but tied together politically) have growing Black or Coloured majorities.

Located some 130 km from Port Elizabeth and 180 km from East London, Grahamstown is also the seat of Rhodes University, a diocese of the Anglican Church of Southern Africa and home to the College of the Transfiguration—the only residential provincial college of the Anglican Church in Southern Africa—and a High Court. However it does not form part of the South African Cities Network.