Year 1465 (MCDXLV) was a common year starting on Tuesday (link will display the full calendar) of the Julian calendar.

For the Robert Browning poem, see Fra Lippo Lippi (poem).

Fra' Filippo Lippi (c. 1406 – 8 October 1469), also called Lippo Lippi, was an Italian painter of the Italian Quattrocento (15th century).

Lippi was born in Florence to Tommaso, a butcher. Both his parents died when he was still a child. Mona Lapaccia, his aunt, took charge of the boy. In 1420 he was registered in the community of the Carmelite friars of the Carmine in Florence, where he remained until 1432, taking the Carmelite vows in 1421 when he was sixteen. In his Lives of the Artists, Vasari says: "Instead of studying, he spent all his time scrawling pictures on his own books and those of others." The prior decided to give him the opportunity to learn painting.

Eventually Fra Filippo quit the monastery, but it appears he was not released from his vows; in a letter dated 1439 he describes himself as the poorest friar of Florence, charged with the maintenance of six marriageable nieces. In 1452 he was appointed chaplain to the convent of S. Giovannino in Florence, and in 1457 rector (Rettore Commendatario) of S. Quirico in Legania, and made occasional, considerable profits; but his poverty seems chronic, his money being spent, according to one account, in frequent amours.

Alessandro di Mariano di Vanni Filipepi, better known as Sandro Botticelli (Italian pronunciation: [ˈsandro bottiˈtʃɛlli]; c. 1445 – May 17, 1510) was an Italian painter of the Early Renaissance. He belonged to the Florentine school under the patronage of Lorenzo de' Medici, a movement that Giorgio Vasari would characterize less than a hundred years later as a "golden age", a thought, suitably enough, he expressed at the head of his Vita of Botticelli. Botticelli's posthumous reputation suffered until the late 19th century; since then his work has been seen to represent the linear grace of Early Renaissance painting. Among his best known works are The Birth of Venus and Primavera.

There are very few details of Botticelli's life, but it is known that he became an apprentice when he was about fourteen years old, which would indicate that he received a fuller education than other Renaissance artists. He was born in the city of Florence in a house in the Via Nuova, Borg'Ognissanti. Vasari reported that he was initially trained as a goldsmith by his brother Antonio. Probably by 1462 he was apprenticed to Fra Filippo Lippi; many of his early works have been attributed to the elder master, and attributions continue to be uncertain. Influenced also by the monumentality of Masaccio's painting, it was from Lippi that Botticelli learned a more intimate and detailed manner. As recently discovered, during this time, Botticelli could have traveled to Hungary, participating in the creation of a fresco in Esztergom, ordered in the workshop of Filippo Lippi by János Vitéz, then archbishop of Hungary.^{[citation needed]}

Pedro de Escobar (c. 1465 – after 1535), a.k.a. Pedro do Porto, was a Portuguese composer of the Renaissance, mostly active in Spain. He was one of the earliest and most skilled composers of polyphony in the Iberian Peninsula, whose music has survived.

He was born at Oporto, Portugal, but nothing is known of his life until he entered the service of Isabella I of Castile in 1489. His surname is of Castilian origin, and maybe he was born to Castilian immigrants, or descendants, established in Porto. But Castilians regarded him as Portuguese.

He was a singer in the Catholic Queen's chapel for ten years, and clearly was working as a composer as well; in addition he was the only member of her chapel described in court records as Portuguese. In 1499 he returned to his native Portugal, but in 1507 received an offer of employment, which he accepted, as the maestro de capilla (chapel master in castilian language) at the cathedral in Seville.

While there he had charge of the choirboys, having to take care of their room and board in addition to having to teach them to sing; he complained of low pay, and eventually resigned. In 1521 he was working in Portugal, as mestre de capela (kapellmeister in Portuguese) for prince Dom Afonso, Cardinal-Infante of Portugal, son of Manuel I of Portugal. His career seems to have ended badly, however, for the final record of his life there is a mention in a document of 1535 that he was an alcoholic and living in squalor. He died in Évora.