The Airbus A300 is a short- to medium-range widebody jet airliner. Launched in 1972 as the world's first twin-engined widebody, it was the first product of Airbus Industrie, a consortium of European aerospace companies, wholly owned today by EADS. The A300 can typically seat 266 passengers in a two-class layout, with a maximum range of 4,070 nautical miles (7,540 km) when fully loaded, depending on model.

Launch customer Air France introduced the type into service on 30 May 1974. Production of the A300 ceased in July 2007, along with its smaller A310 derivative. Freighter sales for which the A300 competed are to be fulfilled by a new A330-200F derivative.

The mission requirements were given in 1966 by Frank Kolk, an American Airlines executive, for a Boeing 727 replacement on busy short- to medium-range routes such as United States transcontinental flights. His brief included a passenger capacity of 250 to 300 seated in a twin-aisle configuration and fitted with two engines, with the capability of carrying full passengers without penalty from high-altitude airports like Denver. American manufacturers responded with widebody trijets, the McDonnell Douglas DC-10 and the Lockheed L-1011 Tristar, as twinjets were banned from many routes by the FAA.