The 2010 congressional elections in Pennsylvania was held on November 2, 2010. Pennsylvania has nineteen seats in the United States House of Representatives. The election was held on the same day as many other PA elections, and the same day as House of Representatives elections in other states. Party primary elections were held May 18, 2010.

Democratic incumbent Bob Brady is the only member of the Pennsylvania delegation who will run unopposed in 2010.

Brady, a long time central figure in the Pennsylvania Democratic Party, has never received less than 74% in a general election, and opponents have had difficult recruiting even moderately electable candidates in this majority-minority district that includes South Philadelphia and some working class suburbs in Delaware County. No Republican has represented this district since 1949. In 2008, he earned 91% of the vote against Mike Muhammad, a teacher who raised no outside funds. Respected for his ability to reach politics deals behind the scenes, Brady has garnered an image as an effective politician, and thus has been rarely challenged by other Democrats. In 2010, Pia Varma, a young freelance writer for conservative publications attempted to gain the Republican nomination, but failed to produce enough signatures to appear on the ballot.

Kermit Barron Gosnell is an American doctor in Philadelphia who ran two multi-million dollar abortion practices, alleged to be fraudulent. After a controversy nearly a year earlier, Gosnell was arrested in January 2011, charged with eight counts of murder: one patient who allegedly died under his care after a botched abortion, and seven infants supposedly born alive whose spinal cords Gosnell allegedly severed with scissors. A grand jury recommended charges of murder against Gosnell and several of his employees.CNN stated in March 2011 that prosecutors were considering seeking the death penalty.

According to press reports, Gosnell graduated from the Jefferson Medical School in 1966, and in 1972 set up shop on Lancaster Avenue in West Philadelphia. The reports say he was well known for providing abortions to poor minority and immigrant women. He allegedly employed his wife, Pearl, at his abortion clinic, and she has since been arrested too. State officials have failed to visit or inspect his abortion clinic since 1993. It is claimed that Gosnell charged $1,600-$3,000 for each late-term abortion. Prosecutors also claim that Gosnell is not certified in either gynecology or obstetrics. The FBI and DEA raided his office in February 2010 and word quickly circulated about the poor and unsanitary conditions inside the building.

Mark Stephen Critz (born January 5, 1962) is the U.S. Representative for Pennsylvania's 12th congressional district, serving since the special election in 2010. He is a member of the Democratic Party.

The district, located in the southwestern portion of the state, stretches from Johnstown to the southern suburbs of Pittsburgh.

Critz was the district director for the 12th's longtime congressman, John Murtha. Following Murtha's death, Critz won the May 2010 special election with 53% of the vote to complete Murtha's term. Critz was sworn in on May 20. Critz won a full term in November 2010 to represent the 12th District in Congress.

Critz was born and raised in Irwin, Pennsylvania, a suburb of Pittsburgh. He is the son of Mary Lou (née Rybacki) and William S. Critz. His father was of Slovak descent, and his mother is of half Polish and half Italian ancestry. In 1987, Critz obtained a Bachelor of Science degree in Management information systems from Indiana University of Pennsylvania in Indiana, Pennsylvania.

Dennis Miller (born November 3, 1953) is an American stand-up comedian, political commentator, actor, sports commentator, and television and radio personality. He is known for his critical assessments laced with pop culture references. He rose to fame as a cast member of Saturday Night Live in 1985, and subsequently hosted a string of his own talk shows on HBO, CNBC and in syndication. He currently hosts a daily, three-hour, self-titled talk radio program, nationally syndicated by Dial Global.

Although in his early years of fame he was perceived to be quite liberal and anti-Republican, in recent years, Miller has become known for his right-leaning political opinions. He is a regular political commentator on Fox News Channel's The O'Reilly Factor in a segment called "Miller Time", and previously appeared on the network's Hannity & Colmes in a segment called "Real Free Speech".

Miller was born in Pittsburgh, Pennsylvania, and grew up in Castle Shannon, a suburb of Pittsburgh, where he graduated from Keystone Oaks High School in 1971. His parents separated and Miller was raised by his mother, Norma, a dietitian. Miller is of Scottish descent. At Point Park University, he majored in journalism because he thought it would be easy: "I remember seeing All the President's Men and thinking Redford looked cool in his crinkled tie."^{[citation needed]} He was a member of Sigma Tau Gamma Fraternity. About his social status during this period, Miller writes: "When I went to college, I lived on campus, and the guys I hung out with made me do some things I'm not proud of, although they made the characters in Revenge of the Nerds look like the Rat Pack in 1962. I myself made that kid Booger look like Remington Steele" (I Rant, Therefore I Am). Miller graduated from Point Park University in 1976.