Har Gobind Khorana

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Great Scientist : Hargobind Khorana Nobel Prize winner

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Duration: 2:04
Updated: 29 Apr 2013

Read text version here http://wp.me/p1tJLH-1q: A story of a small boy who completed his education by sitting under the shadow of a tree and won the most popu...

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Indian Nobel Laureates

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Updated: 15 Jun 2013

'Indian Nobel Laureates' is about the Indians who have won the Nobel prize for their contributions in their respective fields. Personalities like Sir C. V. R...

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UW-Madison's Nobel Prize Winners

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Duration: 14:50
Updated: 13 Jul 2013

This video presents four Nobel winners: Joshua Lederberg (1958, Medicine), Har Gobind Khorana (1968, Medicine), Howard Temin (1975, Medicine), and John Van V...

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Updated: 04 May 2013

Indian origin American scientist Venkataraman Ramakrishnan won the Nobel Prize in Chemistry for the year 2009 for his contributions to ribosome research. He ...

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Nobelpreisträger Des Indiens

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Updated: 08 Jun 2013

Nobelpreisträger Des Indiens 'Indian Nobel Laureates' is about the Indians who have won the Nobel prize for their contributions in their respective fields. Personalities like Sir C. V. Raman,...

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Discussion on Dr Har Gobind Khorana post Matric Scholarships S3

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Duration: 14:56
Updated: 27 Jul 2013

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BORN HERE, "NOBELLED" ABROAD !! :: 1/5 :: "NO-BALLED" AT HOME !!!???

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Duration: 6:16
Updated: 07 Feb 2013

Indian origin American scientist Venkataraman Ramakrishnan won the Nobel Prize in Chemistry for the year 2009 for his contributions to ribosome research. He ...

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Discussion on Dr Har Gobind Khorana post Matric Scholarships S2

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Discussion on Dr Har Gobind Khorana, Post Matric Scholarships S1

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Genetic code - Wiki Article

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Duration: 27:20
Updated: 02 Aug 2013

The genetic code is the set of rules by which information encoded within genetic material is translated into proteins by living cells. Biological decoding is...

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How message RNA is read: duplets, triplets or tetraplets?

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Duration: 4:51
Updated: 06 Oct 2013

The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries. The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code. Not all genetic information is stored using the genetic code. All DNA contains regulatory sequences, intergenic segments, chromosomal structural areas, and other non-coding DNA that can contribute greatly to phenotype. Those elements operate under sets of rules that are distinct from the codon-to-amino acid paradigm underlying the genetic code. Serious efforts to understand how proteins are encoded began after the structure of DNA was discovered by James Watson and Francis Crick, who used the experimental evidence of Maurice Wilkins and Rosalind Franklin, among others. George Gamow postulated that sets of three bases must be employed to encode the 20 standard amino acids used by living cells to build proteins. With four different nucleotides, a code of 2 nucleotides would allow for only a maximum of 42 or 16 amino acids. A code of 3 nucleotides could code for a maximum of 43 or 64 amino acids. The Crick, Brenner et al. experiment first demonstrated that codons consist of three DNA bases; Marshall Nirenberg and Heinrich J. Matthaei were the first to elucidate the nature of a codon in 1961 at the National Institutes of Health. They used a cell-free system to translate a poly-uracil RNA sequence (i.e., UUUUU...) and discovered that the polypeptide that they had synthesized consisted of only the amino acid phenylalanine. They thereby deduced that the codon UUU specified the amino acid phenylalanine. This was followed by experiments in Severo Ochoa's laboratory that demonstrated that the poly-adenine RNA sequence (AAAAA...) coded for the polypeptide poly-lysine and that the poly-cytosine RNA sequence (CCCCC...) coded for the polypeptide poly-proline. Therefore the codon AAA specified the amino acid lysine, and the codon CCC specified the amino acid proline. Using different copolymers most of the remaining codons were then determined. Subsequent work by Har Gobind Khorana identified the rest of the genetic code. Shortly thereafter, Robert W. Holley determined the structure of transfer RNA (tRNA), the adapter molecule that facilitates the process of translating RNA into protein. This work was based upon earlier studies by Severo Ochoa, who received the Nobel Prize in Physiology or Medicine in 1959 for his work on the enzymology of RNA synthesis. Extending this work, Nirenberg and Philip Leder revealed the triplet nature of the genetic code and deciphered the codons of the standard genetic code. In these experiments, various combinations of mRNA were passed through a filter that contained ribosomes, the components of cells that translate RNA into protein. Unique triplets promoted the binding of specific tRNAs to the ribosome. Leder and Nirenberg were able to determine the sequences of 54 out of 64 codons in their experiments. In 1968, Khorana, Holley and Nirenberg received the Nobel Prize in Physiology or Medicine for their work.

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Genes and codons

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Updated: 28 Oct 2013

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SADDI KHETI EP 26 SEG 2

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SADDI KHETI EP 26 SEG 1

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Updated: 28 Jul 2013

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SADDI KHETI EP 27 SEG 2

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SADDI KHETI EP 28 SEG 2

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Duration: 11:35
Updated: 27 Jul 2013

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BORN HERE, "NOBELLED" ABROAD !! :: 4/5 :: "NO-BALLED" AT HOME !!!

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Duration: 3:42
Updated: 27 Aug 2010

Indian origin American scientist Venkataraman Ramakrishnan won the Nobel Prize in Chemistry for the year 2009 for his contributions to ribosome research. He ...

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BORN HERE, "NOBELLED" ABROAD !! :: 2/5 :: "NO-BALLED" AT HOME !!!???

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Duration: 4:49
Updated: 16 Feb 2011

Indian origin American scientist Venkataraman Ramakrishnan won the Nobel Prize in Chemistry for the year 2009 for his contributions to ribosome research. He ...

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BORN HERE, "NOBELLED" ABROAD !! :: 5/5 :: "NO-BALLED" AT HOME !!!

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Duration: 3:56
Updated: 26 Jun 2013

Indian origin American scientist Venkataraman Ramakrishnan won the Nobel Prize in Chemistry for the year 2009 for his contributions to ribosome research. He ...

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SADDI KHETI EP 28 SEG 1

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Bangalore Science Forum_05_july_2012

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Duration: 60:38
Updated: 18 Jul 2013

Speaker: Dr.P.Balaram, Director,Indian Institute of Science Subject: Chemcial Diversity in Biology.

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Notable Nobel Laureates In Cryogenics.wmv

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Updated: 23 Jul 2012

Cryogenic Engineering Department IIT KGP.

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Sir James Black OM

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Updated: 08 Sep 2011

Nobel Laureate, Sir James Black OM - Medical Futures Lifetime Achievement Award Winner 2008.

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U.S. Air Force B-2 stealth bomber flies over near Osan U.S. Air Base in Pyeongtaek

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Obama Sends B-52s, and a Message, to China

Bloomberg

26 Nov 2013

The U.S. decision to fly two B-52s through China's claimed "air defense identification zone" around a set of islands disputed between China and Japan was significant in several ways. First, it was a blunt reminder that Northeast Asia remains the world's most combustible geopolitical hot spot. Second, it's a strong signal that the Barack Obama administration is going to stand by its Asia-Pacific allies against Chinese aggression ... The U.S....(size: 3.3Kb)

photo: DOD Collections Photo

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China says monitored defiant US bomber flights

Herald Tribune

27 Nov 2013

BEIJING - China says it monitored two unarmed U.S. bombers that flew over the East China Sea just days after Beijing declared it was asserting greater military control over the area. Tuesday's flight of the two B-52 bombers underscored that the U.S. will not comply with China's demand that aircraft flying through its newly declared maritime air defense zone identify themselves and accept Chinese instructions ... All rights reserved ... More... ....(size: 3.5Kb)

photo: US Navy / MCS2 Michael Billings

File - U.S. Army and Navy guards cross train while escorting a detainee to a recreational area on board Camp One at Joint Task Force Guantanamo.

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Revealed: Guantanamo suspects were 'turned' into double agents at secret facility

The Independent

27 Nov 2013

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Angola's President Jose Eduardo dos Santos looks on during a banquet hosted by his Portuguese counterpart Anibal Cavaco Silva at the Ajuda palace in Lisbon, Tuesday, March 10, 2009.

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ANGOLA - ISLAM

Voa News

26 Nov 2013

Muslim leaders in Angola say the government has shut down or destroyed dozens of mosques over the past few months, with little or no explanation ... The order said the mosque must be torn down because it was built without authorization ... ....(size: 1.3Kb)

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UW-Madison senior wins Rhodes Scholarship (University of Wisconsin-Madison)

noodls

24 Nov 2013

(Source. University of Wisconsin-Madison). Nov. 24, 2013. University of Wisconsin-Madison senior Drew Birrenkott has been awarded a 2014 Rhodes Scholarship. He joins an elite group of students that have received one of the top honors in higher education. Drew Birrenkott ... That's what this scholarship is really about ... He has studied in India through the biochemistry department's Khorana Program, named for Nobel Prize winner Har Gobind Khorana....(size: 5.0Kb)

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Pranab stress on research - President voices concern over state of higher education ROSHAN KUMAR ...

The Telegraph India

27 Oct 2013

Patna, Oct. 26 ... “There is no Indian university among the top 200 universities in the world ... Why cannot we regain that glory?” he said ... Raman in 1930. “Though we feel the glory of Indian-born literati like Har Gobind Khorana, Subrahmanyan Chandrasekhar and Amartya Sen who won the Nobel Prize in different disciplines, they were not attached to native institutions,” Mukherjee said ... Mukherjee said ... Governor D.Y ... ....(size: 3.0Kb)

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Students to 'evaluate' teachers at Panjab University

Newstrack India

10 Feb 2013

Tweet. Chandigarh, Feb 10 (IANS) Teachers in Panjab University (PU) will soon get some lessons from students with a new teacher feedback system ... "This feedback mechanism will help the quality of teaching and bring positive results ... However, the feedback system is not an evaluation of teachers ... "It is an appreciable effort ... Among its distinguished alumni are Prime Minister Manmohan Singh and Nobel laureate biochemist Har Gobind Khorana ... ).....(size: 3.6Kb)

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Students to 'evaluate' teachers at Panjab Univ

Zeenews

10 Feb 2013

Chandigarh. Teachers in Panjab University (PU) will soon get some lessons from students with a new teacher feedback system ... "This feedback mechanism will help the quality of teaching and bring positive results ... However, the feedback system is not an evaluation of teachers ... "It is an appreciable effort ... Among its distinguished alumni are Prime Minister Manmohan Singh and Nobel laureate biochemist Har Gobind Khorana. IANS ... First Published ... ....(size: 3.1Kb)

photo: PIB of India

The President, Shri Pranab Mukherjee, the President of the Republic of Mauritius, Mr. Rajkeswur Purryag and other dignitaries, at the valedictory function of the 11th Pravasi Bharatiya Divas, in Kochi, Kerala on January 09, 2013,

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Mukherjee lauds Mauritius President, says 'Indian diaspora has made our nation proud'

Newstrack India

09 Jan 2013

Tweet. Kochi, Jan. 9 (ANI). President Pranab Mukherjee on Wednesday said the Indian diaspora has made our nation proud through the significant contributions that they have made to the development of the nations, which they have chosen to make their homes ... " It is a story of many geographies and many histories ... Har Gobind Khorana was awarded the Nobel Prize for medicine in 1968 ... Guru Gobind Singh Marg . Gobind Nagar ... Sarai Gobind ... Khorana ... ....(size: 6.6Kb)

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Reclaiming the ghazal’s space

The Hindu

18 Nov 2012

The culmination of his second term coincided with the end of his neighbour and Nobel laureate Har Gobind Khorana’s stay in the University. While Khorana chose to leave for Massachusetts Institute of Technology (MIT), Narang decided to return to University of Delhi, where he was made professor emeritus in 2005. Recalling Khorana’s farewell ......(size: 4.8Kb)

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Nitish visits religious and cultural sites during Pak tour

Zeenews

16 Nov 2012

Lahore ... Kumar, 61, during his stay, also visited the mausoleum of Mohammad Ali Jinnah to pay homage to the founder of Pakistan ... "The reputation of the Institution is reflected in the illustrious list of alumni which to my pleasure includes names like former Prime Minister Inder Kumar Gujral, Nobel Laureate Dr Har Gobind Khorana, novelist Khushwant Singh and people like Dev Anand and Balraj Sahni among others," he wrote ... PTI ... ....(size: 4.4Kb)

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PM's 'chair' offered to Cambridge professor

Newstrack India

20 May 2012

He left the university later.  ... present leader of Opposition in lok Sabha Sushma Swaraj, her husband and former governor Swaraj Kaushal, Nobel laureate Har Gobind Khorana, astronaut Kalpana Chawla, first Nobel laureate from Pakistan Mohammed Abdus Salam, country's first woman IPS officer Kiran Bedi, Haryana Chief Minister Bhupinder Singh Hooda, Punjab Deputy Chief Minister Sukhbir Singh Badal, Jammu and Kashmir Governor N.N ... ....(size: 5.2Kb)

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Missiles, missiles everywhere

The Times of India

27 Apr 2012

SHARE. AND. DISCUSSTweet Why can't we in India be more business-like? When we tested nuclear weapons in 1998, the government, the media, and the Indian public were spectacularly undignified ... India has had only one that worked in India (C V Raman, who worked in British and not independent India) and three that worked outside India (Har Gobind Khorana, Subramanyan Chandrashekhar and Venkatraman Ramakrishnan, all in the US) ... ....(size: 4.2Kb)

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Death sentences

Indian Express

29 Dec 2011

Whichever way the world of human endeavour stacks up for you, it's hard to dispute the contention that this has been an extraordinary year of passages. Har Gobind Khorana, Kim Jong-il, Dev Anand, M.F. Husain, Steve Jobs, Mansur Ali Khan Pataudi, Shammi Kapoor, Elizabeth Taylor, Vaclav Havel, Bhimsen Joshi, Srilal Shukla, Christopher Hitchens, Socrates ... contd. ....(size: 1.7Kb)

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Memories of another day

The Hindu

26 Dec 2011

Hussain, Zambian President Frederick Chiluba, Betty Ford, former First Lady of the United States, singer Amy Winehouse, actor and director Shammi Kapoor, Wangari Maathai, Nobel Peace Prize winner, ‘Apple Man' Steve Jobs, Marco Simoncelli, Italian motorcycle road racer, boxer Joe Frazier, Har Gobind Khorana, Indian-born American Nobel ......(size: 8.2Kb)

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Professor Har Ghobind Khorana: Biochemist who helped decipher the genetic code and synthesised the first ...

The Independent

24 Nov 2011

Almost anyone studying biology today, "may not know they are studying Khorana, but they are," Andy Greene, a director of the biotechnology and bioengineering centre at the Medical College of Wisconsin, said. Khorana was awarded the 1968 Nobel Prize in ... Khorana was born in 1922 in Raipur, a village in Punjab ... Har Gobind Khorana, scientist....(size: 2.0Kb)

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Khorana was an exceptional visionary

Deccan Herald

20 Nov 2011

On November, 9, 2011 the world witnessed the silent departure of a great scientific revolutionary, Prof Har Gobind Khorana, a man renowned for cracking the code to life. Born in a small village in Punjab (now in Pakistan), Har Gobind was the youngest of five siblings. Despite poor financial condition, his father’s desire to educate his children laid the foundation for Khorana’s glorious academic career....(size: 5.6Kb)

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Make changes yourself !

Great Scientist : Hargobind Khorana Nobel Prize winner

Indian Nobel Laureates

UW-Madison's Nobel Prize Winners

BORN HERE, "NOBELLED" ABROAD !! :: 3/5 :: "NO-BALLED" AT HOME !!!

Nobelpreisträger Des Indiens

Discussion on Dr Har Gobind Khorana post Matric Scholarships S3

BORN HERE, "NOBELLED" ABROAD !! :: 1/5 :: "NO-BALLED" AT HOME !!!???

Discussion on Dr Har Gobind Khorana post Matric Scholarships S2

Discussion on Dr Har Gobind Khorana, Post Matric Scholarships S1

Genetic code - Wiki Article

How message RNA is read: duplets, triplets or tetraplets?

Genes and codons

SADDI KHETI EP 26 SEG 2

SADDI KHETI EP 26 SEG 1

SADDI KHETI EP 27 SEG 2

SADDI KHETI EP 28 SEG 2

BORN HERE, "NOBELLED" ABROAD !! :: 4/5 :: "NO-BALLED" AT HOME !!!

BORN HERE, "NOBELLED" ABROAD !! :: 2/5 :: "NO-BALLED" AT HOME !!!???