Heparin-Induced Thrombocytopenia (HIT) is a rare but serious reaction to heparin, leading to a significant drop in platelet count and an increased risk of thrombosis. It occurs when the immune system forms antibodies against heparin-platelet factor 4 (PF4) complexes. Key clinical features include a drop in platelets and thrombosis within 5–14 days of heparin exposure. Diagnosis involves clinical criteria and confirmatory tests like the serotonin release assay. Treatment focuses on stopping heparin and starting non-heparin anticoagulants. Early detection and management are crucial to preventing complications. #HeparinInducedThrombocytopenia #thrombocytopenia #thrombosis #hit #platelets This video is NOT sponsored. Some product links are affiliate links, which means if you buy something, we'll receive a small commission. ====================================================== Buy the best medical text books we follow (affiliate links): ====================================================== 1. Harrison's Principles of Internal Medicine, Twenty-First Edition (Vol.1 & Vol.2) : https://amzn.to/4bEumzN 2. Davidson's Principles and Practice of Medicine 24th Edition: https://amzn.to/3VZHTfF 3. Kumar and Clark's Clinical Medicine 10th Edition: https://amzn.to/3Y1wM8M 4. First Aid for the USMLE Step 1 2024 34th Edition: https://amzn.to/4cZTZft =========================== ⏰ Timecodes ⏰ =========================== 00:00 - Introduction 00:30 - Type I HIT 00:54 - Type II HIT 01:24 - Epidemiology of HIT 01:59 - Pathophysiology of HIT 03:03 - Clinical features of HIT 03:17 - Diagnosis of HIT 03:46 - 4T scoring system of HIT (Table) 04:11 - Blood Tests (PF4-Heparin Antibody test, Serotonin release assay) 04:35 - Complications of HIT 05:05 - Treatment of HIT 07:00 - References =========================== Links for Related Videos: =========================== 1. Amiodarone And Thyroid Dysfunction [Thyrotoxicosis & Hypothyroidism]: https://youtu.be/GZyQbPq_cN4 2. Drug Induced Lupus Erythematosus : https://youtu.be/BDEuJ6re-jY 3. Types of Adverse Drug Reactions (ADRs): https://youtu.be/F3IE_HQWANk 4. Cytochrome P450 Inducers: https://youtu.be/aBeUli3UbAE 5. Cytochrome P450 Inhibitors: https://youtu.be/eXLumbwJdxE =========================== Links for related playlists: =========================== 0. Hematology & Oncology: https://www.youtube.com/playlist?list=PLbilivK1P_9La4mgSmbsYqefVN97MQiZZ 1. Mnemonics:https://www.youtube.com/playlist?list=PLbilivK1P_9LxDii1hRMDej0BspYPu6ai 2. High Yield: https://www.youtube.com/playlist?list=PLbilivK1P_9KrZLVym2_xeIeGjlpQ4SJP 3. Simple Explanations: https://www.youtube.com/playlist?list=PLbilivK1P_9IgDVBrE5XMojpEfrDrZUnu 4. Clinical Signs: https://www.youtube.com/playlist?list=PLbilivK1P_9LlONCaOSDDdUHTdnU8XkpN 5. Lectures: https://www.youtube.com/playlist?list=PLbilivK1P_9JDMfiInhZN1UmcAtYbbEPC 6.Gastroenterology: https://www.youtube.com/playlist?list=PLbilivK1P_9LgsoOnRJAKTh3hjOc81xqH 7. All Playlists: https://www.youtube.com/view_all_playlists ---------------------------------------------------------------------------------------------------------------------------------------------------------- Many current and future clinicians learn from Extensive Medicine. We have updated tools and materials to prepare you to succeed in medical school, competitive exams (like AMC, USMLE, MRCP, NCLEX, and PLAB), and as a future clinician. =========================== Subscribe to our channel:https://www.youtube.com/channel/UCtU1y_tzgmhzV5qQj9Blb2A?sub_confirmation=1 =========================== =========================== Connect with us ! ============================= Get early access to our upcoming video releases, practice questions, giveaways, and more when you follow us on social media: Facebook:https://www.facebook.com/extensivemedicine/ https://www.facebook.com/ExtensiveMedicalMCQs/ Twitter: https://twitter.com/EM_Medicine Check our website: https://www.extensivemedicine.net For suggestions and queries: extensivemedicine@gmail.com =========================== Medical disclaimer! =========================== Extensive Medicine (EM) does not provide medical advice. EM does not provide a diagnosis or other recommendation for treatment and is not a substitute for the professional judgment of a healthcare professional in the diagnosis and treatment of any person. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.

• published: 13 Aug 2024
• views: 95