The Greater Accra Region is the smallest of Ghana's 10 administrative regions in terms of area, occupying a total land surface of 3,245 square kilometres or 1.4 per cent of the total land area of Ghana. In terms of population, however, it is the second most populated region, after the Ashanti Region, with a population of 2,905,726 in 2000, accounting for 15.4 per cent of Ghana’s total population. The Greater Accra region also harbors the seat of government in the capital city of Accra.

In 1960, Greater Accra, then referred to as Accra Capital District, was geographically and legally part of the Eastern Region. It was, however, administered separately by the Minister responsible for local government. With effect from 23 July 1982, Greater Accra was created by the Greater Accra Region Law (PNDCL 26) as a legally separate region to include the Ada local council area.

The Greater Accra region is bordered on the north by the Eastern Region, on the east by the Volta Region, on the south by the Gulf of Guinea, and on the west by the Central Region. It is smallest region in the country in total area, and is made up of 10 districts.

Accra /əˈkrɑː/ is the capital and largest city of Ghana, with an estimated urban population of 2,291,352 as of 2012^[update]. Accra is also the capital of the Greater Accra Region and of the Accra Metropolitan District, with which it is coterminous. Accra is furthermore the anchor of a larger metropolitan area, the Greater Accra Metropolitan Area (GAMA), which is home to about 4 million people, making it the largest metropolitan conglomeration in Ghana by population, and the eleventh-largest metropolitan area in Africa.

Accra stretches along the Ghanaian Atlantic coast and extends north into the country's interior. Originally built around a port, it served as the capital of the British-ruled Gold Coast between 1877 and 1957. Once merely a 19th-century suburb of Victoriaborg, Accra has since transitioned into a modern metropolis; the city's architecture reflects this history, ranging from 19th-century British colonial buildings to modern skyscrapers and apartment blocks.

Accra is Ghana's primate city, serving as the nation's economic and administrative hub. It is furthermore a centre of culture and tourism, sporting a wide range of nightclubs, restaurants and hotels. Since the early 1990s, a number of new buildings have been built, including the multi-storey French-owned Novotel hotel. The city's National Theatre was built with Chinese assistance. In 2010, the GaWC designated Accra a Gamma-minus-level world city, indicating a growing level of international influence and connectedness.