TP-003
TP-003 is an anxiolytic drug with a novel chemical structure, which is used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. It is a subtype-selective partial agonist at GABAA receptors, binding to GABAA receptor complexes bearing either α2, α3 or α5 subunits, but only showing significant efficacy at α3. It has modest anticonvulsant activity although less than that of diazepam, and its main effect is likely to be selective anxiolytic action, as seen with other related α3-preferring agonists such as L-838,417.
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Podcasts:
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by UB40
D.U.B
by: UB40When me reach me yard me got one thing on me mind,
To hold me little woman and fe make her feel irie.
Be play album, dub plate, and forty-five
For dat's the kind of riddim that keeps me alive.
Me turn on fe me radio some a chat 'bout dat
But I know more than D.J. so I nah play you dat.
[Chorus:]
Me tek a 'D' and a 'U' an' a 'B' - not 'E'
That thing there is special to me.
Me listen in the morning, also in the night
For dat form of music is out-a-sight.
The newest form of music is easy to see
It start with a 'D' and end with a 'B'
Dub in a de morning and dub in a de night
Mek the whole neighbourhood feel alright,
feel alright
When me reach me yard me got one thing on me mind,
To hold me little woman and fe mek her feel irie.
When me reach me yard me got one thing on me mind,
To hold me little woman and fe mek her feel irie.
[Chorus]
Rock in a de dance, me seh fe give dub a chance,
Rock in de blues, you know you jus' can't lose.
A dub me a defend, on dub i can depend
Check out dis yah music and run tell yo' friend.
We don't want rock 'n' roll and we got enough soul,
We don't want rock 'n' roll and we got enough soul.
Bass is beutiful if it's clean,
But dis yah dub music, man it well mean.
No bother follow friend and ignore dub again.
It's simple, but effective, can't you see?
A lot of people catch on in 'eighty-three.
Now is 'eighty-four and you must know the score,
Anything me chat, you know the people bawl 'more.'
Me jump 'pon de graphics, don't get vex'
All me have a total concept to make you feel Irie.