Tizanidine has been found to be as effective as other antispasmodic drugs and have superior tolerability than baclofen and diazepam. Tizanidine may cause hypotension, so caution is advised when it is used in patients who have a history of orthostatic hypotension. Use caution with this drug as it can be very strong even at the 2 mg dose. Also use caution when switching from gel cap to tablet form and vice versa.
Tizanidine can occasionally cause liver damage, generally the hepatocellular type. Clinical trials show that up to 5% of patients treated with tizanidine had elevated liver function test values, though symptoms disappeared upon withdrawal of the drug. Care should be used when first beginning treatment with tizanidine with regular liver tests for the first 6 months of treatment.
Tizanidine is supplied as 2 and 4 mg tablets for oral administration, and in gel cap form in doses of 2 mg, 4 mg, and 6 mg.
The tablets are composed of the active ingredient, tizanidine hydrochloride (2.288 mg equivalent to 2 mg tizanidine base and 4.576 mg equivalent to 4 mg tizanidine base), and the inactive ingredients, silicon dioxide colloidal, stearic acid, microcrystalline cellulose and anhydrous lactose.
It has a Volume of Distribution of 2.6L/Kg (Manufacturers notes).
Category:Muscle relaxants Category:Alpha-adrenergic agonists Category:Imidazolines Category:Organochlorides Category:Benzothiadiazoles
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Name | Ted Leo |
---|---|
Birth name | Theodore Francis Leo |
Background | solo_singer |
Born | September 11, 1970, South Bend, Indiana, United States |
Genre | Pop punk, indie rock, Hardcore punk, Thrashcore, Mod revival, Powerpop |
Occupation | Singer, songwriter, guitarist |
Years active | 1989–present |
Label | Ace Fu, Gern Blandsten, Lookout!, Touch and Go, Matador Records |
Url | www.tedleo.com |
Associated acts | Citizens Arrest, Chisel, The Sin-Eaters, Ted Leo and the Pharmacists |
Theodore Francis "Ted" Leo (born September 11, 1970, in South Bend, Indiana) is an American punk rock/indie rock singer, songwriter, and guitarist. Leo has played with many bands, including Citizens Arrest, Chisel, the Sin-Eaters, and Ted Leo and the Pharmacists, his current group.
Leo grew up in Bloomfield, New Jersey. He graduated from Seton Hall Preparatory School in West Orange in 1988 and the University of Notre Dame in the fall of 1993 with a degree in English. His brothers Chris Leo and Danny Leo are also singer-songwriters, and members of Native Nod, The Lapse, The Van Pelt, Vague Angels and Holy Childhood. He is a vegan.
Ted is a fan of and frequent contributor to WFMU, most notably to Tom Scharpling's "The Best Show on WFMU." In 2007, he rewrote and performed The Jam's "That's Entertainment" as a tribute to the station.
He is also active in the reformed lineup of Citzens Arrest.
Category:1970 births Category:Living people Category:American male singers Category:Musicians from Indiana Category:American indie rock musicians Category:American vegans Category:Mod revival Category:Musicians from New Jersey Category:People from Bloomfield, New Jersey Category:People from South Bend, Indiana Category:Seton Hall Preparatory School alumni Category:University of Notre Dame alumni Category:American punk rock singers Category:American punk rock guitarists
This text is licensed under the Creative Commons CC-BY-SA License. This text was originally published on Wikipedia and was developed by the Wikipedia community.
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