Ephedrine ( /ɨˈfɛdrɪn/ or /ˈɛfɨdriːn/; not to be confused with ephedrone) is a sympathomimetic amine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia.

Ephedrine is similar in structure to the (semi-synthetic) derivatives amphetamine and methamphetamine. Chemically, it is an alkaloid derived from various plants in the genus Ephedra (family Ephedraceae). It works mainly by increasing the activity of noradrenaline on adrenergic receptors. It is most usually marketed in the hydrochloride and sulfate forms.

In Traditional Chinese Medicine, the herb má huáng (麻黄, Ephedra sinica) contains ephedrine and pseudoephedrine as its principal active constituents. The same is true of other herbal products containing extracts from some of the other Ephedra species.

Ephedrine exhibits optical isomerism and has two chiral centres, giving rise to four stereoisomers. By convention the enantiomers with opposite stereochemistry around the chiral centres (1R,2S and 1S,2R) are designated ephedrine, while pseudoephedrine has same stereochemistry around the chiral carbons (1R,2R and 1S,2S).

Factory 81 was an American rock band from Detroit, Michigan. Formed in 1997, the band was active until 2003.

The band had not initially decided on a name until Nathan Wallace wore a shirt bearing a patch which read "Factory 81", and the rest of the band thought that "it sounded good", deciding that this would be the name of their band.

Factory 81 released their only album, Mankind in 1999 on Medea Records; while it did not chart, it was reissued by The Orchard in 2000 and Universal Motown Republic Group on October 3, 2000. In 2001, the album was reissued by the independent record label Mojo Records. Factory 81 also appeared on the compilation Take a Bite Outta Rhyme: A Rock Tribute to Rap, contributing a cover of Cypress Hill's "Insane in the Brain". The compilation peaked at #195 on the Billboard 200. In November 2000, Factory 81 toured alongside Mudvayne, Kittie and Apartment 26. The band signed to Jive Records, but left the label in 2002. In 2003, bassist Kevin Lewis and drummer Andy Cyrulnik left the group, prompting Factory 81 to disband.