All about Phencyclidine. This is another Text 2 Audio transformation using Flite. Below is the transcript for the recording: Phencyclidine , commonly initialized as PCP and known colloquially as angel dust, KJ , illy, or wet, is a recreational dissociative drug. Formerly used as an anesthetic agent, PCP exhibits hallucinogenic effects. First synthesized in 1926, it was eventually patented in 1952 by the Parke-Davis pharmaceutical company and marketed under the brand name Sernyl. In chemical structure, PCP is an arylcyclohexylamine derivative, and, in pharmacology, it is a member of the family of dissociative anesthetics. PCP works primarily as an NMDA receptor antagonist, which blocks the activity of the NMDA receptor and, like most antiglutamatergic hallucinogens, is significantly more dangerous than other categories of hallucinogens. Other NMDA receptor antagonists include ketamine, tiletamine, dextromethorphan and nitrous oxide. As a recreational drug, PCP may be ingested, smoked, or inhaled.

• published: 26 Sep 2013
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