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Cyclopentamine (Clopane, Cyclonarol, Cyclosal, Cyklosan, Nazett, Sinos) is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was indicated in the past as an over-the-counter (OTC) medication for use as a nasal decongestant, notably in Europe and Australia, but has now been largely discontinued possibly due to the availability, effectiveness, and safety of a structurally similar drug, propylhexedrine.[citation needed]

Cyclopentamine is the cyclopentane homologue of propylhexedrine, differing only in terms of the contracted ring size of a cyclopentane, containing one -CH2- unit less than the cyclohexyl group.

In terms of the acyclic part of the molecule, both cyclopentamine and propylhexedrine are directly synonymous with methamphetamine, all three molecules containing the 2-methylaminopropyl side-chain. The obvious difference between them is that whereas methamphetamine is an aromatic molecule containing a phenyl group, cyclopentamine and propylhexedrine are entirely aliphatic and contain no delocalized electrons at all. The effect that this has on potency is that the reduced alicyclic-alkylamines are weaker than unsaturated (meth)amphetamine.

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This page contains text from Wikipedia, the Free Encyclopedia - http://en.wikipedia.org/wiki/Cyclopentamine

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