Imipramine (sold as Antideprin, Deprimin, Deprinol, Depsol, Depsonil, Dynaprin, Eupramin, Imipramil, Irmin, Janimine, Melipramin, Surplix, Tofranil), also known as melipramine, is an antidepressant medication, a tricyclic antidepressant of the dibenzazepine group. Imipramine is mainly used in the treatment of major depression and enuresis (inability to control urination).

It has also been evaluated for use in panic disorder.

Imipramine is used in the treatment of depression, such as depression associated with agitation or anxiety and has similar efficacy to the antidepressant drug moclobemide.

Imipramine was, in the late 1950s, the first tricyclic antidepressant to be developed (by Ciba). It was first tried against psychotic disorders, such as schizophrenia, but proved insufficient. As an antidepressant, it did well in clinical studies and it is known to work well in even the most severe cases of depression. It is not surprising, therefore, that Imipramine is also known to cause a high rate of manic and hypomanic reactions, especially in patients with preexisting bipolar disorder. It is estimated that up to 25% of such patients maintained on Imipramine will switch into mania or hypomania. Such powerful antidepressant properties have made it favorable in the treatment of treatment-resistant depression.

Jason Bermas was born July 24, 1979 in Hollywood, Florida. He studied at SUNY Oneonta located in Oneonta, NY, where he currently lives. Bermas is also a filmmaker, and has played a large role in the creation of many controversial films such as Fabled Enemies, Loose Change and Invisible Empire.

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Carl Michael Edwards II (born August 15, 1979) is a NASCAR driver. He currently drives the #99 Fastenal, Aflac, Kellogg's, Best Buy, and UPS Ford Fusion in the NASCAR Sprint Cup Series for Roush Fenway Racing. He won the Busch Series championship in 2007 and nearly won the Sprint Cup Series title in 2011, but lost by a tiebreaker.

Edwards' big break came in 2002, when he competed in 7 NASCAR Craftsman Truck Series events for MB Motorsports. His best finish in the seven races was 8th at Kansas Speedway. He also ran one Busch Series race for Bost Motorsports, finishing 38th at Gateway International Raceway. However, it was enough to impress Jack Roush, and Edwards became a full-time Truck Series competitor in 2003, driving the #99 Ford F-150 sponsored by Superchips. He won Rookie-of-the-Year honors in addition, to three race wins, eventually finishing 8th in the points standings at the end of the season. In 2004, he notched three more race wins, including the season-opening Florida Dodge Dealers 250 at the Daytona International Speedway. At season's end, Edwards finished 4th in the points. In August 2004, he made his NEXTEL Cup Series debut, replacing Jeff Burton, who left the team, in the No. 99 Ford Taurus for Roush Racing, at the Michigan International Speedway. He finished 10th. He drove the #99 Ford for the remainder of the 2004 NEXTEL Cup. He also once again ran one Busch Series race; this time for Bobby Benton's RAB Racing team at Bristol Motor Speedway with sponsorship from Mac Tools.