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- 2-Aminotetralin
- 2-Benzylpiperidine
- 2C-B-BZP
- 3,4-Dihydroxystyrene
- 3-Iodotyrosine
- 4-Benzylpiperidine
- 4-Fluoroamphetamine
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- 6-Hydroxydopamine
- Abanoquil
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- RS-97,078
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- SB-269,970
- Schizophrenia
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- SEP-225,289
- SEP-227,162
- Sercloremine
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- SKF-64139
- SKF-7698
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Idazoxan (INN) is a drug which is used in scientific research. It acts as both a selective α2 adrenergic receptor antagonist, and an antagonist for the imidazoline receptor. Idazoxan has been under investigation as an antidepressant, but it did not reach the market as such. More recently, it is under investigation as an adjunctive treatment in schizophrenia. Due to its alpha-2 receptor antagonism it is capable of enhancing therapeutic effects of antipsychotics, possibly by enhancing dopamine neurotransmission in the prefrontal cortex of the brain, a brain area thought to be involved in the pathogenesis of schizophrenia.
This page contains text from Wikipedia, the Free Encyclopedia -
http://en.wikipedia.org/wiki/Idazoxan
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
