The Bedlam Series (officially known for sponsorship purposes as The Oklahoma Farm Bureau Bedlam Series) refers to the athletics rivalry between the University of Oklahoma Sooners and the Oklahoma State University Cowboys, of the Big 12 Conference. Both schools were also members of the Big 8 Conference before the formation of the Big 12 Conference in 1996, and both were divisional rivals in the Big 12 South Division prior to 2011.

The Bedlam Series is, like most other intrastate rivalries, a rivalry that goes beyond one or two sports. Both schools also have rivalries with other schools, though most of those rivalries are limited to one or two sports at the most. The rivalry is all the more intense since their games often decide the conference championship.

While the football and basketball games stand today as the marquee events in the Bedlam Series, the term "Bedlam" actually began with the rivalry between the schools' prestigious wrestling programs, more particularly the raucous crowds that attended the matches held at Oklahoma State's Gallagher-Iba Arena.