Piss Christ is a 1987 photograph by artist and photographer Andres Serrano. It depicts a small plastic crucifix submerged in a glass of the artist's urine. The piece was a winner of the Southeastern Center for Contemporary Art's "Awards in the Visual Arts" competition, which is sponsored in part by the National Endowment for the Arts, a United States Government agency that offers support and funding for artistic projects. A print of the photograph was damaged using a screwdriver or icepick on April 17, 2011 while on exhibit in Avignon, France.

The photograph is of a small plastic crucifix submerged in a glass of what appears to be a yellow liquid. The artist has described the substance as being his own urine. The photograph was one of a series of photographs that Serrano had made that involved classical statuettes submerged in various fluids—milk, blood, and urine. The photograph is a 60x40 inch Cibachrome print. It is glossy and its colors are deeply saturated. The presentation is that of a golden, rosy medium including a constellation of tiny bubbles. Without Serrano's explanation, the viewer would not necessarily be able to differentiate between the stated medium of urine and a medium of similar appearance, such as amber or polyurethane.

Andres Serrano (born August 15, 1950 in New York City) is an American photographer and artist who has become notorious through his photos of corpses and his use of feces and bodily fluids in his work, notably his controversial work "Piss Christ", a red-tinged photograph of a crucifix submerged in a glass container of what was purported to be the artist's own urine.

Serrano is from a half Honduran, half Afro-Cuban background, and was raised a strict Roman Catholic. He studied from 1967 to 1969 at the Brooklyn Museum and Art School.

He worked as an assistant art director at an advertising firm, before creating his first works in 1983. Serrano is represented in New York, where he lives and works, and Paris, by Yvon Lambert Gallery.

His work has been exhibited in diverse locations around the world including the Episcopal Cathedral of Saint John the Divine in New York City, World without end (2001), and a retrospective at the Barbican Arts Centre in London, Body and soul (2001).

His exhibitions have often inspired angry reactions. On October 5, 2007, several of his works were vandalized at an art gallery in Lund, Sweden by people who were believed to be part of a neo-Nazi group. On April 16, 2011, after two weeks of protests and a campaign of hate mail and abusive phone calls to an art gallery displaying his work, orchestrated by groups of French Catholic fundamentalists, approximately a thousand people marched through the streets of Avignon, to protest outside the gallery. On April 17, 2011, two of his works, Piss Christ and The Church, were vandalized. The gallery director plans to reopen the museum with the damaged works on show "so people can see what barbarians can do".