Children of Mana, known in Japan as Seiken Densetsu DS: Children of Mana (聖剣伝説DS CHILDREN of MANA, Seiken Densetsu DS: Chirudoren obu Mana^?, lit. "Holy Sword Legend DS: Children of Mana"), is a 2006 action role-playing game for the Nintendo DS handheld game console, part of the Mana series and, more specifically, of the World of Mana project launched by Square Enix. Children of Mana is the first game of the World of Mana and was developed by Nex Entertainment under the supervision of Koichi Ishii.

In the middle of the island of Illusia stands the famous Tree of Mana. Several years ago, a great disaster took place at the base of the tree and many lives were lost, leaving the main characters as orphans. A brave young boy and girl used the Sword of Mana to save the world from disaster. Now, years later, the main characters set out to investigate the details of the event that took so many loved ones away from them.

It was released on March 2, 2006 in Japan and was subsequently released on October 30, 2006, and January 12, 2007, in North America and Europe, respectively. It received mixed reviews, with generally positive reviews in Japan and negative ones in the United States.