Marvel 2099 is a Marvel Comics imprint, started in 1992, that explores one possible future of the Marvel Universe. It was originally announced by Stan Lee in his "Stan's Soapbox" column as a single series entitled The Marvel World of Tomorrow, which was being developed by Lee and John Byrne. This later changed to a line of books under the banner Marvel 2093 (the date being one hundred years from the year in which the titles launched) before finally being published as Marvel 2099. The three of the initial four titles launched — Doom 2099, Punisher 2099, and Spider-Man 2099 — starred futuristic takes on pre-existing characters. The fourth, Ravage 2099, featured an all-new superhero, scripted for several months by Stan Lee. The 2099 line soon expanded to include 2099 Unlimited, Fantastic Four 2099, Ghost Rider 2099, Hulk 2099, X-Men 2099, and X-Nation 2099.

The initial universe began with Spider-Man 2099, Ravage 2099, Doom 2099, and Punisher 2099 being launched in subsequent months. Peter David wrote Spider-Man for the bulk of the series, and it was consistently the most popular series.^{[citation needed]} It satirized corporations, with Spider-Man constantly clashing with Alchemax, which employed him in his secret identity and was run by his father. Stan Lee wrote the first eight issues of Ravage as an extremely political story about corruption, corporate pollution, and the environment. After Lee left, he was replaced by a series of writers who failed to provide consistent direction for the book.^{[citation needed]} Doom, believing himself to be the true Doctor Doom, began a lengthy quest to re-conquer Latveria. The Punisher largely dealt with corporate crimes and people who were rich enough to buy their way out of any other punishment.

Spider-Man 2099 is a fictional character, a comic book superhero created by Peter David and Rick Leonardi in 1992 for Marvel Comics' Marvel 2099 line. His secret alter ego is Miguel O'Hara, a brilliant geneticist living in New York in the year 2099 A.D. who is attempting to recreate the abilities of the original Spider-Man in other people and later suffers a related accident that causes half his DNA to be re-written with a spider's genetic code. O'Hara is the first Latino Spider-Man.

Spider-Man 2099 is a direct result of the 30th anniversary of Spider-Man's first appearance. Spider-Man 2099 was one of the many Marvel characters to be re-imagined for the Marvel 2099 comic book line that showed future versions of classic Marvel characters living in the year 2099, a century after the current Marvel Universe time period (the Marvel 2099 timeline began its run in 1992, approximately 107 years prior to the year in which the new books would take place). Spider-Man 2099 was first featured in a five page sneak preview of the first issue of his then-upcoming series in the 30th anniversary issue of The Amazing Spider-Man. The Spider-Man 2099 series' first issue appeared shortly afterward. When originally published, the Marvel 2099 stories were meant to depict the official future of the Marvel Universe: a dystopian America governed by corrupt megacorporations with a number of cyberpunk elements.