De'Anthony Thomas (born January 5, 1993) is an American college football running back. He is a student at the University of Oregon and plays on its football team, the Oregon Ducks. He previously attended Crenshaw High School in Los Angeles, California, where he played running back, defensive back, and wide receiver.

Thomas rushed for 1,299 yards and 18 touchdowns on offense and collected five interceptions on defense, while leading Crenshaw (12-2) to its second straight city championship. Regarded as a five-star recruit by Rivals.com, Thomas was listed as the No. 1 athlete prospect in the class of 2011.

Thomas is also a sprinter, with a personal best of 10.57 seconds in the 100 meters and 20.61 seconds in the 200 meters.

During his time at Crenshaw, he was given the nickname "Black Mamba" by Snoop Dogg and also played in his football league The SYFL (Snoop Youth Football League)

Thomas had a standout 2011 season as a true Freshman for Oregon. He amassed a staggering 2,235 all-purpose yards, while his season haul of 18 touchdowns reset the school record for number of touchdowns by a true Freshman.